Senior Statistical Programmer Lead — SDTM/ADaM Expert

Syneos Health; Indiana (PA); On-site; USD 120,000 - 170,000; Full time

Job summary

Syneos Health is seeking a Principal Statistical Programmer with 8+ years of clinical/SAS programming experience to lead programming activities across studies. You will develop SDTM/ADaM datasets, define specifications, and support safety analyses while ensuring CDISC compliance.

Strong leadership and cross-functional collaboration are essential in this role. Join a team that values innovation, accountability, and delivering high-quality results in a dynamic environment.

Qualifications

• 8+ years of relevant clinical/SAS/Statistical programming experience.
• SME level review capabilities at an experienced Senior level profile.
• Lead experience of min 1+ year with proven project management.
• Strong understanding of CDISC standards and clinical domain.

Responsibilities

• Develop and validate SDTM/ADaM datasets and TLFs.
• Prepare specifications and generate Define.XML, ADRG, SDRG.
• Support safety and efficacy analyses across studies.
• Collaborate with cross-functional teams and lead clinical study trials.
• Contribute to e-submissions and CDISC compliance.

Skills

SAS programming

Clinical trial experience

CDISC standards

Leadership/mentoring

Communication skills

Tools

SAS

ADaM/Define.XML

Job description

Syneos Health is seeking a Principal Statistical Programmer with 8+ years of clinical/SAS programming experience to lead programming activities across studies. You will develop SDTM/ADaM datasets, define specifications, and support safety analyses while ensuring CDISC compliance.

Strong leadership and cross-functional collaboration are essential in this role. Join a team that values innovation, accountability, and delivering high-quality results in a dynamic environment.