Senior Software Engineer

Xilis; Durham (NC); Remote; USD 90,000 - 150,000; Full time

Job summary

An innovative biotech company is seeking a Senior Software Engineer to enhance their cutting-edge MicroOrganoSphere technology. This role involves designing and developing device software that integrates complex hardware systems, enhancing therapeutic precision for cancer patients. You will collaborate with cross-functional teams to drive innovation, creating robust data pipelines and intuitive user interfaces. Join a forward-thinking organization committed to transforming cancer care through advanced technology, where your contributions will directly impact patient outcomes and drug discovery efforts. This is a unique opportunity to be part of a team that values diverse backgrounds and perspectives.

Benefits

Comprehensive health plans

Vision and dental insurance

Retirement plans

Unlimited PTO

Qualifications

• 7+ years of software engineering experience focused on embedded systems.
• Strong understanding of hardware-software integration and real-time processing.

Responsibilities

• Integrate sensors and hardware components using manufacturer libraries.
• Develop software logic systems for error detection and response.
• Create data pipelines to synchronize device data with AWS.

Skills

Python

Embedded Systems

Hardware-Software Integration

Data Acquisition

API Development on AWS

Linux Systems

CI/CD Pipelines

Git Version Control

Education

Bachelor's in Electrical Engineering

Bachelor's in Computer Engineering

Tools

AWS

Git

Linux

Job description

Xilis, Inc. is an innovation-driven biotech company developing its proprietary MicroOrganoSphere ("MOS") Technology for functional precision oncology. Xilis' MOS Technology enables rapid and scalable generation of patient tumor models that retain patient-specific tumor biology and tumor microenvironment, representing one of the most translationally-relevant ex vivo technologies for precision oncology drug discovery and development. Located in Research Triangle Park, Durham, NC, Xilis is building a functional precision medicine platform that incorporates scaled multi-modal profiling of therapeutic activity and AI / ML-enabled analytics to catalyze functional precision medicine drug discovery, development and diagnostics. Collectively, Xilis aims to harness its MOS Platform to enable development of the most effective therapeutics and guide them to the right patients at the right time.

Impact

Your work will directly contribute to advancing cancer care through innovative technology. Our proprietary MOS hardware is a sophisticated microscale encapsulation system for manipulating and studying complex 3D tissue models, combining microfluidics, extracellular matrices, robotics, and specialized protocols. Xilis As Senior Software Engineer, you will play a crucial role in enhancing this revolutionary platform that guides precision therapy for cancer patients and accelerates drug discovery and development.

Main Objectives

• Design, develop, and support the device software for our revolutionary MicroOrganoSphere (MOS) technology
• Enhance device capabilities by implementing sensor integration and data collection systems that maximize device efficiency and performance
• Develop additional applications and features to support MOS creation and functional assays
• Collaborate with cross-functional hardware engineering and data science teams to drive innovation in our tech platform

Responsibilities

• Integrate diverse sensors and hardware components using manufacturer libraries and SDKs
• Develop and design software logic systems for error detection, handling, and response, based on system readouts from hardware components
• Create robust data pipelines to synchronize device data with our AWS data lake
• Build intuitive, responsive on-device user interfaces
• Implement comprehensive logging and monitoring systems for device operations
• Collaborate with data scientists to develop and deploy device-specific algorithms that enhance operational efficiency and output quality
• Troubleshoot and resolve software issues to ensure reliable device operation, including PCBs and onboard computers
• Develop and maintain standard operating procedures (SOPs) for device operation to support laboratory workflows

Requirements

• 7+ years of professional software engineering experience focused on embedded systems, device drivers, and integration with hardware components.
• Strong understanding of hardware-software integration, embedded systems, real-time processing, and how to interface with physical devices (e.g., sensors, actuators, communication buses, PCBs, microcontrollers).
• Proficiency in Python for instrument control, data acquisition, and device communication protocols
• Experience building and integrating APIs on AWS
• Experience with Git version control, CI / CD pipelines, and agile development
• Experience with Linux systems
• Bachelor's degree in Electrical Engineering, Computer Engineering, or related technical field

Preferred Qualifications

• Background in life sciences or biotechnology
• Knowledge of regulatory requirements for laboratory instrumentation
• Background in electrical engineering or hands-on experience with hardware fundamentals such as signal processing, circuit-level debugging, or hardware bring-up.
• Prior experience with microfluidics or lab automation systems
• Experience with C / C++ for performance-critical applications
• Knowledge of UI / UX design principles for instrumentation interfaces

Xilis was created when its three founders - an engineer, a physician, and a biologist - decided to come together and commercialize their technology to transform cancer care. We are committed to building a team that represents a variety of backgrounds, perspectives, and skills. We do not discriminate on the basis of race, color, ancestry, religion, sex, national origin, sexual orientation, age, citizenship, marital status, disability, gender identity, or Veteran status. Furthermore, even if your work experience isn't perfectly aligned with what we've described above, if you're excited about what we're building then we want to talk to you!

Xilis offers comprehensive health, vision, dental & retirement plans, and unlimited PTO. We are a remote-friendly team : our headquarters are in Durham, North Carolina, but we have team members across the US (and beyond!).

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Senior Software Engineer • Durham, NC, United States