Senior Scientist, Viral Vector Drug Product

Azalea Therapeutics; Berkeley (CA); On-site; USD 125,000 - 170,000; Full time

Benefits offered by this job

Bonus eligibility

Equity eligibility

Job summary

Azalea Therapeutics seeks a Scientist II/Senior Scientist I to lead drug product and downstream development for viral vectors, reporting to the VP Process Development. You will design stability studies, develop formulation buffers, and drive filtration strategies with scale-down models, serving as the technical drug product expert during GMP campaigns.

The role emphasizes cross‑functional collaboration with Analytical Development, Manufacturing, Quality, Regulatory, and CDMOs, plus mentoring of

Qualifications

• PhD or MS with relevant industry experience required.
• Experience in drug product development for biologics or viral vectors.
• Experience with DoE and formulation optimization.
• GMP/cGMP manufacturing exposure preferred.

Responsibilities

• Design, execute, and interpret internal stability studies and in-use compatibility assessments.
• Develop and optimize formulation buffers/excipients for viral vectors.
• Investigate mechanisms of vector loss of function and propose mitigations.
• Lead filtration strategy selection and scale-down modeling.
• Collaborate with CDMOs to optimize manufacturing processes and tech transfer.
• Partner with Analytical Development, Manufacturing, QA, Regulatory, and Supply Chain; present recommendations to CMC leadership.

Skills

DoE formulation studies

Independent experimental design

Scientific communication

Mentoring scientists

Cross-functional collaboration

Problem solving in biotech

Adaptability in startup biotech

Education

PhD in Chemical Eng./Bioeng./Pharmaceutics/Biochem./BME or related

MS with 5+ years relevant industry experience

Tools

DoE statistical analysis

Vector titer assays

DLS/SEC/UV stability tools

Job description

Azalea Therapeutics seeks a Scientist II/Senior Scientist I to lead drug product and downstream development for viral vectors, reporting to the VP Process Development. You will design stability studies, develop formulation buffers, and drive filtration strategies with scale-down models, serving as the technical drug product expert during GMP campaigns.

The role emphasizes cross‑functional collaboration with Analytical Development, Manufacturing, Quality, Regulatory, and CDMOs, plus mentoring of