Senior Scientist, Spatial Immunology & MSI

St. Jude Children's Research Hospital; Memphis (TN); On-site; USD 104,000 - 186,160; Full time

Job summary

St. Jude Children's Research Hospital in Memphis invites a Scientist or Sr. Scientist to lead spatial metabolomics and immunophenotyping efforts, overseeing MALDI-MSI instrument operations, method development, sample prep, data acquisition, and analysis.

The role emphasizes integrating spatial metabolomics with spatial transcriptomics and proteomics, collaborating with cores, preparing grants and manuscripts, and guiding lab personnel.

Qualifications

• Bachelor's degree in a relevant scientific area is required.
• Ten (10) years of relevant work experience for Senior Scientist; Eight (8) years with a Master’s; Five (5) years with a PhD.

Responsibilities

• Develop, execute, and oversee specialized methods for mapping metabolites, lipids, proteins/peptides, and other small molecules in diverse immune and tumor microenvironments.
• Oversee daily operations, calibration, optimization, and routine maintenance of core MALDI/DESI imaging mass spectrometers.
• Analyze complex spatial metabolomics and related datasets, integrate with multi-omics datasets as needed, and interpret tissue features and biological insights.
• Coordinate multiple aspects of research projects and execute laboratory experiments utilizing appropriate laboratory techniques.
• Draft sections of research manuscripts and grants as directed.
• Provide technical support for ongoing projects, including maintaining datasets and lab documentation.

Skills

MALDI MSI

MSI data analysis

Immunology

Tissue metabolomics

Multi-omics

Education

Bachelor's degree

Tools

MALDI/DESI imaging mass spectrometers

DESI imaging

Job description

St. Jude Children's Research Hospital in Memphis invites a Scientist or Sr. Scientist to lead spatial metabolomics and immunophenotyping efforts, overseeing MALDI-MSI instrument operations, method development, sample prep, data acquisition, and analysis.

The role emphasizes integrating spatial metabolomics with spatial transcriptomics and proteomics, collaborating with cores, preparing grants and manuscripts, and guiding lab personnel.