Senior Scientist - Protein Expression Sciences

BioSpace; Village of Tarrytown (NY); On-site; USD 110,000 - 179,000; Full time

Job summary

Regeneron seeks a Senior Scientist for the Protein Expression Sciences Department in Tarrytown, NY. You will create antibody production cell lines using mammalian expression technologies and develop new methods to advance the expression platform, collaborating with cross-functional teams in a fast-growing scientific environment.

The role requires a PhD with postdoc experience or BS/MS with several years in immunology/biology, strong cell culture and flow cytometry skills, and the ability to

Qualifications

• PhD with 0–3 years postdoc experience or BS/MS with 4–8 years in Immunology, Cell Biology or Molecular Biology.
• Hands-on experience in cell culture, flow cytometry and antibody staining.
• Experience with PCR, cloning and related molecular biology techniques.
• Ability to work independently, manage multiple tasks and collaborate with cross-functional teams.
• Interest in leading new scientific directions and working in a fast-paced environment.

Responsibilities

• Apply mammalian expression technologies to generate regulatory-compliant stable cell lines.
• Perform aseptic cell culture, handling, and transfection of cell lines.
• Conduct flow cytometry assays and operate Hamilton platforms.
• Perform molecular biology and protein biochemistry techniques including PCR, cloning, SDS-PAGE and western blotting.
• Design and analyze multicolor flow cytometry experiments.
• Analyze and present data at team and department meetings.
• Maintain accurate records of experiments and data analysis.

Skills

Cell culture

Flow cytometry

Molecular biology

PCR

Cloning

Data analysis

Education

PhD in Immunology/Cell Biology/Molecular Biology

Tools

Hamilton liquid handler

SDS-PAGE

Western blotting

Job description

Build Our Future Together

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a highly motivated Senior Scientist to join our Protein Expression Sciences Department. In this role, you will create antibody production cell lines using state-of-the-art mammalian expression technologies and develop new technologies to further advance our expression platform, while collaborating with cross-functional scientific teams. This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & Where

• Location: Tarrytown, NY
• Work model: On-site

Discover Your Role

• Apply innovative mammalian expression technologies to generate regulatory-compliant stable cell lines
• Perform aseptic cell culture, handling, and transfection of cell lines
• Conduct flow cytometry assays and operate liquid handler platforms (Hamilton) to analyze stable cell lines
• Perform molecular biology and protein biochemistry techniques, including PCR, RT-PCR, plasmid sub-cloning, isolation of genomic DNA and RNA from CHO cells, SDS-PAGE, and western blotting
• Independently design, conduct, and analyze multicolor flow cytometry experiments
• Analyze and present data at smaller team and broader department meetings
• Maintain complete, accurate, and timely records of experiments and data analysis

This Role Requires

• PhD with 0-3 years of postdoctoral experience, or BS/MS with 4-8 years of experience, in Immunology, Cell Biology, or Molecular Biology
• Hands-on technical experience in cell culture, flow cytometry, and antibody staining
• Experience with molecular biology techniques such as PCR and cloning
• Passion for innovation and a desire to lead new scientific directions
• Working independently, demonstrating strong problem-solving skills and the ability to manage multiple tasks efficiently without direct supervision
• Strong desire to develop your skills and work with a cross-functional team and the ability to thrive in a collaborative, fast-paced environment
• Experience with gene editing, lentivirus infections, CRISPR library workflows, and NGS is a plus

Does this sound like you?

We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$109,900.00 - $179,300.00