Scientist CRISPR Screening, target identification

BioSpace; Village of Tarrytown (NY); On-site; USD 94,000 - 153,000; Full time

Job summary

Regeneron in Tarrytown, NY is seeking a Scientist to join the Oncology & Immuno-Oncology group, supporting identification and validation of tumor targets using in vitro and in vivo approaches. You will design and execute cell-based and animal studies that inform target discovery and validation, collaborating with your supervisor and peers to move science forward.

This role offers an opportunity to contribute to a fast-growing scientific organization dedicated to meaningful patient impact, with

Qualifications

• BS or MS in a relevant field with 3+ years of work experience.
• Experience with mouse tumor models (subcutaneous implantation, dosing, harvest).
• Experience with large-scale mammalian cell culture.
• Experience with basic molecular biology and biochemistry techniques.
• Strong organization and communication, team player.
• Desirable: FACS panel design and multi-color analysis.
• Desirable: CRISPR screening experience.

Responsibilities

• Perform in vitro cell culture and molecular biology experiments to support target discovery.
• Conduct in vivo tumor studies in mice and collect data from tissues.
• Analyze and document data rigorously and communicate findings clearly.
• Compile results into polished, presentation-ready formats.
• Maintain precise lab notebooks and manage lab supplies.

Skills

Mouse tumor models

Mammalian cell culture

Molecular biology techniques

Organizational skills

Communication skills

FACS panel design

CRISPR screening

Education

BS or MS in relevant field

Job description

Build Our Future Together

At Regeneron, we use science and innovation to develop life-changing medicines for people with serious diseases. We are seeking a Scientist to join our Oncology & Immuno-Oncology group, supporting the identification and validation of novel tumor drug targets using in vitro and in vivo approaches. In this role, you will design and execute cell-based and animal studies that directly inform target discovery and validation, while collaborating closely with your supervisor and cross-functional peers to move promising science forward.

This position offers the opportunity to contribute to a fast-growing, science-driven organization making a meaningful difference to patients worldwide.

When & Where

• Location: Tarrytown, NY
• Work model/flexibility: Onsite

Discover Your Role

• Perform in vitro cell culture and molecular biology experiments to support target discovery
• Conduct in vivo tumor studies in mice, including injections, and blood and tissue collection
• Analyze and document data with rigor, then communicate findings clearly to your supervisor and peers
• Compile and organize results into polished, presentation-ready formats
• Maintain precise, well-organized lab notebooks
• Keep the lab running smoothly through daily maintenance tasks, such as ordering reagents and supplies
• Thrive in a fast-paced, team-driven environment where priorities can shift day to day
• Bring curiosity and initiative to learning new techniques and expanding your skill set

This Role Requires

• BS or MS with at least 3 years of relevant work experience
• Experience with mouse tumor models, including subcutaneous implantation, drug dosing, tumor measurement, and tumor harvest
• Experience with large-scale mammalian cell culture
• Experience with basic molecular biology and biochemistry techniques (e.g., cell/tissue lysate preparation for DNA/RNA/protein analysis, western blots, transfection, PCR, and cloning)
• Strong organizational and communication skills, with the ability to work well in a team
• Preferred: experience designing FACS panels and performing multi-color FACS analysis
• Preferred: experience with CRISPR screening.

Does this sound like you? We are committed to building a workplace with an inclusive culture. Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law. Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits. Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits. For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually)

$93,900.00 - $153,300.00

Please be advised that at Regeneron, we believe we do our best work when we are together. For that reason, many roles are required to be performed onsite.