Senior Scientist, Process Development – Biologics & LC/MS

Biopharma Careers; Cambridge (MA); On-site; USD 126,000 - 171,000; Full time

Benefits offered by this job

Retirement plan

Annual bonus program

Stock-based incentives

Flexible time off

Job summary

Amgen is seeking a Process Development Senior Scientist – Attribute Sciences in Cambridge, MA. You will develop and transfer analytical methods to monitor critical quality attributes, lead advanced protein characterization, and drive robust, automation-ready workflows that improve efficiency and data quality.

The role requires a PhD or equivalent (or a Master’s with experience) with deep LC/MS expertise and regulatory documentation experience.

Qualifications

• PhD or equivalent with strong analytical skills in biotechnology.
• Experience with peptide mapping, disulfide mapping, and intact mass analysis preferred.
• Ability to translate complex data into regulatory documentation and technical reports.

Responsibilities

• Develop, optimize, transfer analytical methods for monitoring quality attributes.
• Lead late-stage protein characterization and structure elucidation studies.
• Establish automated analytical workflows to reduce hands-on time and improve lab efficiency.
• Interpret data and author technical/regulatory documentation for INDs/BLAs.
• Provide SME guidance to cross-functional partners.

Skills

Analytical method development

LC/MS analysis

Regulatory communication

Data interpretation

Education

Doctorate degree

Master’s degree + 2 years experience

Bachelor’s degree + 4 years experience

Tools

Thermo Orbitrap

Chromeleon

Biopharma Finder

Automation software

Job description

Amgen is seeking a Process Development Senior Scientist – Attribute Sciences in Cambridge, MA. You will develop and transfer analytical methods to monitor critical quality attributes, lead advanced protein characterization, and drive robust, automation-ready workflows that improve efficiency and data quality.

The role requires a PhD or equivalent (or a Master’s with experience) with deep LC/MS expertise and regulatory documentation experience.