Senior Process Development Scientist - Analytical Chemistry

Amgen Inc. (IR)

Thousand Oaks, Northern (CA, KY)

Hybrid

USD 126,000 - 171,000

Full time

14 days+

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Job summary

Amgen Inc. is seeking a Process Development Senior Scientist to define quality attributes and advance analytical methods for protein therapeutics.

You will develop LC-MS/MS based workflows, characterize modifications such as glycosylation and oxidation, and optimize chromatography/electrophoresis strategies within a collaborative analytical group. You will communicate complex concepts, maintain accurate records, and drive studies to meet deadlines while contributing to patents and publications

Qualifications

  • PhD in Analytical Chemistry or Biochemistry with mass spectrometry focus.
  • 2+ years post-PhD in pharma/biotech process & product analytical development.
  • Experience peptide mapping and LC-MS identification/quantification of mods.
  • Experience with Thermo Q-Exactive, Agilent and Waters platforms.

Responsibilities

  • Define favorable quality attributes and optimize analytical tools for development.
  • Develop and apply sample prep and analytical methods for proteins/molecules (LC-MS/MS).
  • Assess quality attributes and chemical modifications in proteins.
  • Collaborate with multidisciplinary teams and communicate results clearly.
  • Maintain electronic lab notebooks and contribute to patents/publications.

Skills

Mass spectrometry
Analytical chemistry
Biochemistry
Chromatography
Electrophoresis
R/Python
Data analysis

Education

PhD in Analytical Chemistry
MS in Biochemistry

Tools

Thermo Q-Exactive MS
Agilent MS
Agilent UHPLC/HPLC
Waters UHPLC/HPLC
Empower
Chromeleon
BiopharmaFinder
Mass Hunter

Job description

Amgen Inc. is seeking a Process Development Senior Scientist to define quality attributes and advance analytical methods for protein therapeutics.

You will develop LC-MS/MS based workflows, characterize modifications such as glycosylation and oxidation, and optimize chromatography/electrophoresis strategies within a collaborative analytical group. You will communicate complex concepts, maintain accurate records, and drive studies to meet deadlines while contributing to patents and publications

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