Senior Scientist – Preclinical Safety Profiling Lab

Novartis Group Companies; Cambridge (MA); On-site; USD 99,000 - 192,000; Full time

Job summary

Novartis Group of Companies in Cambridge, MA is seeking a Preclinical Safety Profiling Laboratory Associate at Senior Scientist I or II level. You will join our PCS team to advance early safety screening and translational safety assessment, supporting drug discovery through preclinical development.

The role offers a dynamic, collaborative environment where you will deploy state-of-the-art laboratory science and data exploration methods to accelerate innovative medicines.

Qualifications

• BS with 5+ years of relevant work experience in pharmacology/toxicology.
• MVSc/MS/M.Pharm with 2+ years of relevant work experience in pharmacology/toxicology.
• Understands the basic concepts of hazard identification and risk assessment.
• Familiar with early drug discovery processes.
• Excellent communication skills and ability to translate analytical concepts for diverse audience and stakeholders.

Responsibilities

• Perform in-vitro biochemical and cell-based experiments to support teams to clarify and mitigate off-target activities leading to go or no go decisions.
• Maintain cell lines and provide support for ongoing experiments.
• Independently develop assays to implement project strategy.
• Experience with radioactivity is advantageous.
• Experience with working with stand-alone automation and readers (e.g. Felix, ECHO, CELL, Envision, Microbeta).
• Interest in identifying and evaluating new assay technologies.
• The role is central to our support of all small molecule projects from early discovery phases through to preclinical candidates and beyond.
• Effectively communicate with stakeholders, including experimental design, data quality and timeline requirements.
• Participate in cross-functional early safety screening & profiling collaborations with Novartis Biomedical Research partners to support the early derisking of compounds, drug targets, and therapeutic modalities
• Deliver clear and concise presentations for audiences with different expertise
• Ensure quality and compliance of data generation, analyses and resultant reports

Skills

Analytical thinking

Data analysis

Communication skills

Collaboration

Team player

Problem solving

Education

BS with 5+ years experience in pharmacology/toxicology

MVSc/MS/M.Pharm with 2+ years experience in pharmacology/toxicology

Job description

Novartis Group of Companies in Cambridge, MA is seeking a Preclinical Safety Profiling Laboratory Associate at Senior Scientist I or II level. You will join our PCS team to advance early safety screening and translational safety assessment, supporting drug discovery through preclinical development.

The role offers a dynamic, collaborative environment where you will deploy state-of-the-art laboratory science and data exploration methods to accelerate innovative medicines.