Senior Scientist – Pharmaceutical Materials Scientist

SmartRecruiters, Inc.

Groton, Northern (CT, KY)

On-site

USD 45,000 - 52,000

Full time

8 days ago
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Benefits offered by this job

Medical benefits
Dental benefits
Vision benefits
Life insurance
Disability insurance
401(k) with company match
Paid vacation

Job summary

Eurofins Scientific, based in Groton, CT, is seeking a Senior Scientist – Pharmaceutical Materials Scientist to lead advanced solid-state characterization of large bRo5 molecules and develop innovative screening strategies. The role involves collaboration with Medicinal Chemistry, Formulation, and Biopharmaceutics to align solid form selection with clinical study goals.

Responsibilities include applying crystallization techniques, contributing to new methodologies, and ensuring proper

Qualifications

  • Master's Degree (MS) with 2+ years of experience or a PhD in pharmaceutical science, chemistry, chemical engineering, or related field.
  • Experience in pharmaceutical solid state characterization techniques (XRD, PLM, DSC, TGA, spectroscopy) with strong data analysis.
  • Experience with infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR.
  • Experience solving materials science problems for large molecules using experimental approaches and collaboration.
  • Experience with amorphous solid dispersion strategies and innovative screening strategies.

Responsibilities

  • Conduct advanced solid-state characterization of large bRo5 molecules.
  • Apply novel crystallization techniques to recrystallize bRo5 molecules.
  • Support multidisciplinary teams to define crystallization, polymorph, salt, and co-crystal screening activities.
  • Collaborate to define screening and characterization strategies for solid form selection in clinical studies.
  • Solve scientific problems using contemporary Materials Science techniques.
  • Contribute to development of new scientific approaches within Materials Science.
  • Maintain accurate electronic lab notebook entries per good practice.

Skills

Solid-state characterization
Data analysis
Communication
Independent work

Education

Master's Degree (MS) with 2+ years of experience
PhD in pharmaceutical science or related field

Tools

X-ray powder diffraction
Polarized light microscopy
DSC/TGA
FTIR/NIR/FT-Raman
SSNMR

Job description

Senior Scientist – Pharmaceutical Materials Scientist
  • Full-time
  • Compensation: USD 33.75 - USD 38.5 - hourly

Eurofins Scientific is an international life sciences company, providing a unique range of analytical testing services to clients across multiple industries, to make life and our environment safer, healthier and more sustainable. From the food you eat, to the water you drink, to the medicines you rely on, Eurofins laboratories work with the biggest companies in the world to ensure the products they supply are safe, their ingredients are authentic and labelling is accurate.

The Eurofins network of companies is the global leader in food, environment, pharmaceutical and cosmetic product testing and in agroscience Contract Research Organisation services. It is one of the market leaders in certain testing and laboratory services for genomics, discovery pharmacology, forensics, advanced material sciences and in the support of clinical studies, as well as having an emerging global presence in Contract Development and Manufacturing Organisations. It also has a rapidly developing presence in highly specialised and molecular clinical diagnostic testing and in-vitro diagnostic products.

In over 30 years, Eurofins has grown from one laboratory in Nantes, France to 58,000 staff across a decentralised and entrepreneurial network of 900 laboratories in over 54 countries. Eurofins companies offer a portfolio of over 200,000 analytical methods to evaluate the safety, identity, composition, authenticity, origin, traceability and purity of biological substances and products.

In 2021, Eurofins generated total revenues of EUR 6.72 billion, and has been among the best performing stocks in Europe over the past 20 years.

We are seeking a highly innovative Materials Scientist with deep expertise in non-traditional solid-form strategies for beyond Rule-of-5 (bRo5) molecules, including PROTACs, RIPTACs, and molecular glues. This role will support the design of advanced solid form screening approaches, amorphous solid dispersion (ASD) formulations, predictive mathematical models. The position is based in Groton, CT (USA).

Role Responsibilities:
  • Conduct advanced solid-state characterization of large bRo5 molecules of pharmaceutical relevance.
  • Apply novel crystallization techniques to recrystallize bRo5 molecules.
  • Support multidisciplinary project teams and collaborate with colleagues to define and implement crystallization, polymorph, salt, and co-crystal screening activities according to project timelines.
  • Collaborate with colleagues in Medicinal Chemistry, Formulation and Biopharmaceutics to define and implement screening and characterization strategies consistent with solid form selection for clinical studies.
  • Solve scientific problems using contemporary Materials Science experimental techniques.
  • Contribute to the development of new scientific approaches and knowledge within the Materials Science organization.
  • Ensure contemporaneous and accurate entries are made in the electronic laboratory notebook system according to accepted good practice.
Requirements
  • Master's Degree (MS) with 2+ years of experience or a PhD in pharmaceutical science, chemistry, chemical engineering, or related field.
  • Experience in pharmaceutical solid state characterization techniques (such as x-ray powder diffraction, polarized light microscopy, differential scanning calorimetry, thermogravimetric analysis, spectroscopy, etc.). Strong data analysis and interpretation skills.
  • Experience and understanding of infrared spectroscopy (FTIR, NIR, FT-Raman) and/or SSNMR.
  • Experience with solving Materials Science problems related to large molecules, e.g., solid state chemistry and particle characterization using experimental approaches and team collaboration.
  • Experience with amorphous solid dispersion strategies and ability to develop innovative solid form screening strategies.
  • Understanding of physical, analytical, and organic chemistry.
  • Good organizational skills, the ability to work independently, and excellent oral and written communication skills are required.
  • Experience in mathematical modeling.
    • The position is full-time, M- F 8 am to 5 pm
    • May be requested to work on weekends, overtime, and holidays based on business needs.
    • Candidates currently living within a commutable distance of Groton, CTare encouraged to apply.
    • Excellent full-time benefits, including comprehensive medical coverage, dental, and vision options
    • Life and disability insurance
    • 401(k) with company match
    • Paid vacation and holidays
    • #LI-EB1

Eurofins USA PSS Insourcing Solutions is a Disabled and Veteran Equal Employment Opportunity employer.

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