Senior Scientist, Oligonucleotide DP & External Manufacturing

Judo Bio; Cambridge (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Judo Bio in Cambridge, MA is seeking a Senior Scientist to lead injectable formulation development for siRNA programs, reporting to CMC leaders. You will drive DP formulation design, analytical characterization, and external scale-up with CDMOs.

This role interfaces with internal teams and external partners to advance pipeline programs, author CMC documentation, and support IND-enabling activities in a fast-paced, collaborative environment.

Qualifications

• PhD or equivalent experience in pharmaceutical sciences or related field.
• 4–8+ years of industry experience in formulation development for biotech/pharma.
• Experience with oligonucleotide and conjugate formulations is a plus.
• Familiarity with phase-appropriate CMC development and regulatory documentation is required.

Responsibilities

• Design and build internal lab capabilities for oligonucleotide DP formulation development.
• Plan and execute DP formulation development studies for phase-appropriate DP presentation.
• Prepare and evaluate injectable formulations for preclinical studies (rodent and NHP).
• Support analytical characterization of critical DS/DP properties.
• Coordinate activities with internal teams and external CDMOs for process development and scale-up.
• Author CMC documentation and support IND-enabling regulatory work.

Skills

Formulation design

Oligonucleotides

External collaboration

Regulatory documentation

Education

PhD in Pharmaceutical Sciences

MS with substantial industry experience

Tools

HPLC/LC-MS

Job description

Judo Bio in Cambridge, MA is seeking a Senior Scientist to lead injectable formulation development for siRNA programs, reporting to CMC leaders. You will drive DP formulation design, analytical characterization, and external scale-up with CDMOs.

This role interfaces with internal teams and external partners to advance pipeline programs, author CMC documentation, and support IND-enabling activities in a fast-paced, collaborative environment.