Senior Scientist: Nuclear Receptor & Chemical Biology

St. Jude; Lauderdale Courts (TN); On-site; USD 104,000 - 186,000; Full time

Job summary

St. Jude Children's Research Hospital in the United States seeks a Scientist or Senior Scientist to lead multidisciplinary efforts on PXR and CAR modulation using cell biology, molecular biology, and chemical biology approaches.

You will design experiments, generate high-quality data, and collaborate with structural biologists and medicinal chemists. The role emphasizes independent project leadership, publication track record, and potential involvement in manuscripts and grant-supported work.

Qualifications

• Bachelor's degree in a relevant scientific area required.
• PhD in cell biology, molecular biology, chemical biology, pharmacology, or related field strongly preferred.
• Ten plus years of research experience for Senior Scientist level; multiple high-impact publications.

Responsibilities

• Designs and executes experiments under the PI or senior scientist direction.
• Develops new research protocols and methods.
• Interprets data, summarizes results, and maintains data quality.
• May publish as co-author and present findings at meetings.
• Oversees lab operations, equipment, and supplies; trains staff.
• Maintains regular, predictable attendance.

Skills

Cell biology

Molecular biology

Chemical biology

Small molecules MOA

Structural biology concepts

Medicinal chemistry basics

Murine studies

Education

Bachelor's degree in life sciences

PhD in relevant field

Job description

St. Jude Children's Research Hospital in the United States seeks a Scientist or Senior Scientist to lead multidisciplinary efforts on PXR and CAR modulation using cell biology, molecular biology, and chemical biology approaches.

You will design experiments, generate high-quality data, and collaborate with structural biologists and medicinal chemists. The role emphasizes independent project leadership, publication track record, and potential involvement in manuscripts and grant-supported work.