Senior Scientist, Molecular Diagnostics & RT-qPCR

Molecular Designs, LLC; Birmingham (AL); On-site; USD 75,000 - 110,000; Full time

Job summary

Molecular Designs is seeking a hands‑on molecular biologist to join the Birmingham, AL team as a scientist focused on RT‑qPCR/qPCR assay optimization for infectious disease applications. The role emphasizes assay-level design, performance improvements, and robust analytical validation.

The ideal candidate will contribute from primer/probe design through analytical validation, with experience in master mix formulation considered a plus, and will collaborate with cross‑functional teams to ensure

Qualifications

• Design and optimize RT-qPCR/qPCR assays for infectious disease diagnostics.
• Lead analytical validation studies (LoD, specificity, cross-reactivity, precision, linearity).
• Ensure studies comply with regulatory/ISO requirements.
• Mentor junior scientists and present findings to stakeholders.

Responsibilities

• Develop and optimize primers and probes for multiplex real‑time PCR assays.
• Troubleshoot assay performance issues (amplification efficiency, non‑specific amplification, cross‑reactivity).
• Lead analytical validation studies (LoD, specificity, precision, linearity, interference).
• Ensure regulatory/ISO compliance across workflows.
• Mentor team members and review experimental design and data interpretation.
• Present findings to internal stakeholders and partners.

Skills

Primer/probe design

qPCR optimization

Analytical validation

Troubleshooting

Regulatory compliance

Mentoring

Data interpretation

Education

Four-year degree in basic sciences

Tools

Master mix formulation

Job description

Molecular Designs is seeking a hands‑on molecular biologist to join the Birmingham, AL team as a scientist focused on RT‑qPCR/qPCR assay optimization for infectious disease applications. The role emphasizes assay-level design, performance improvements, and robust analytical validation.

The ideal candidate will contribute from primer/probe design through analytical validation, with experience in master mix formulation considered a plus, and will collaborate with cross‑functional teams to ensure