Senior Scientist, Large Molecule Bioanalysis (LC/MS)

IQVIA; Indianapolis (IN); On-site; USD 120,000 - 180,000; Full time

Job summary

IQVIA Laboratories in Indiana seeks a Senior Scientist, Large Molecule Bioanalytical to organize, curate, and scientifically evaluate LC/MS data from early drug discovery ADME studies. You will translate complex datasets into actionable insights that support compound profiling and lead optimization.

The role requires 3–7+ years of LC/MS experience in discovery ADME/DMPK, strong data-quality mindset, and collaboration across cross-functional teams to improve pipelines and reporting.

Qualifications

• Bachelor's or master's degree in analytical chemistry, pharmacokinetics, pharmaceutical sciences, biochemistry, or related field.
• 3–7+ years of experience working with LC/MS data in discovery stage ADME or DMPK settings.
• Strong understanding of LC/MS workflows and quantitative data analysis.
• Experience evaluating data quality and identifying artifacts.
• Familiarity with high-resolution mass spectrometry bioanalytical data for large molecules or biomarkers.

Responsibilities

• Manage and curate LC/MS datasets from non-regulatory ADME bioanalysis studies supporting exploratory and pilot toxicology in vivo PK/PD studies.
• Ensure accuracy, completeness, consistency, and traceability of data from raw LC/MS outputs through processed results and internal reports.
• Perform scientific quality-control reviews to identify outliers, errors, and artifacts.
• Evaluate ADME parameters across compounds, projects, and assay formats to support SAR and structure-property relationships.
• Collaborate with DMPK, analytical, informatics, and project teams to interpret data and improve pipelines and visualization tools.

Skills

LC/MS data analysis

ADME/DMPK experience

Data quality assessment

Cross-functional collaboration

Education

Analytical chemistry / pharmacokinetics / biochemistry degree

Tools

LC/MS workflows

Job description

IQVIA Laboratories in Indiana seeks a Senior Scientist, Large Molecule Bioanalytical to organize, curate, and scientifically evaluate LC/MS data from early drug discovery ADME studies. You will translate complex datasets into actionable insights that support compound profiling and lead optimization.

The role requires 3–7+ years of LC/MS experience in discovery ADME/DMPK, strong data-quality mindset, and collaboration across cross-functional teams to improve pipelines and reporting.