Senior Scientist, Large Molecule Bioanalytical

IQVIA LLC; Indianapolis (IN); On-site; USD 64,000 - 134,000; Full time

Job summary

IQVIA Laboratories in Indiana seeks a Senior Scientist, Large Molecule Bioanalytical to organize, curate, and scientifically evaluate LC/MS data generated in early drug discovery ADME studies. You will ensure datasets are accurate, traceable, and translated into insights that support compound profiling and lead optimization.

The role requires 3–7+ years of LC/MS experience in discovery ADME or DMPK settings, strong data-analysis skills, and collaboration with bioanalytical, informatics, and

Qualifications

• Organize and evaluate LC/MS data from non-regulatory ADME bioanalysis studies.
• Ensure accuracy, completeness, consistency, and traceability of data from raw LC/MS outputs through reports.
• Perform quality-control reviews to identify outliers, errors, and artifacts.
• Evaluate ADME parameters across compounds, projects, and assay formats to support SAR/SPR.
• Collaborate with DMPK, analytical, informatics, and project teams to interpret data and improve pipelines and visualization tools.
• Coordinate internal and external CRO data contributions while aligning study designs and outputs.
• Prepare clear summaries, tables, figures, dashboards, and data packages to support progression and portfolio decisions.
• Establish standardized data formats, naming conventions, metadata practices, and reproducible workflows.

Responsibilities

• Manage and curate LC/MS datasets from ADME studies.
• Ensure data accuracy, completeness, and traceability across outputs and reports.
• Perform scientific QC to identify artifacts and data issues.
• Collaborate with cross-functional teams to interpret data and improve analysis pipelines.
• Coordinate CRO data contributions and maintain metadata alignment.
• Prepare discovery data packages to support compound progression.

Skills

LC/MS data analysis

Data interpretation

Cross-functional collaboration

Quality control

Education

Bachelor’s or Master’s degree in analytical chemistry

Tools

Mass spectrometry

LC/MS workflows

Job description

We are seeking a Senior Scientist, Large Molecule Bioanalytical to join IQVIA Laboratories in Indiana. We hire passionate innovators who drive healthcare forward through thoughtful and inclusive collaboration. If you want to discover a career with greater purpose, join us as we transform and accelerate research and development.

Job Summary:

Organize, curate, and scientifically evaluate large molecule, new modality, and biomarker LC/MS data generated in early drug discovery ADME studies. Ensure that complex datasets are accurate, consistent, traceable, and translated into actionable insights that support compound profiling, lead optimization, and data-driven program decisions.

What You'll Be Doing:

• Manage and curate LC/MS datasets from non-regulatory ADME bioanalysis studies supporting exploratory and pilot toxicology in vivo PK/PD studies
• Ensure the accuracy, completeness, consistency, and traceability of data from raw LC/MS outputs through processed results and internal reports
• Perform scientific quality-control reviews to identify outliers, errors, and analytical or method-related artifacts
• Evaluate ADME parameters across compounds, projects, and assay formats to support structure-activity and structure-property relationships
• Collaborate with DMPK, analytical, informatics, and project teams to interpret data and improve pipelines, automation, visualization tools, and analytical efficiency
• Coordinate internal and external CRO data contributions while maintaining alignment among study designs, metadata, analytical methods, and final outputs
• Prepare clear summaries, tables, figures, dashboards, and integrated discovery data packages to support compound progression and portfolio decisions
• Establish standardized data formats, naming conventions, metadata practices, and reproducible workflows for downstream analysis and knowledge sharing

What We Are Looking For:

• Bachelor’s or master’s degree in analytical chemistry, pharmacokinetics, pharmaceutical sciences, biochemistry, or a related scientific field
• 3–7+ years of experience working with LC/MS data in discovery stage ADME or DMPK settings
• Strong understanding of LC/MS workflows, quantitative data analysis, and common discovery ADME assays
• Experience evaluating data quality and identifying analytical, method-related, and data-processing artifacts
• Familiarity with high-resolution mass spectrometry bioanalytical data and workflows for large molecules, new drug modalities, or biomarkers
• Other Equivalent combination of education, training, and experience may be accepted in lieu of degree

The Knowledge, Skills and Abilities Needed for This Role:

• Strong analytical thinking and the ability to translate complex scientific datasets into clear, actionable insights
• Scientific rigor, attention to detail, and a strong data-integrity mindset when managing complex datasets
• Effective cross-functional collaboration with bioanalytical scientists, DMPK teams, project coordinators, study directors, CROs, informatics teams, and IT partners
• Ability to communicate data assumptions, limitations, trends, inconsistencies, and conclusions clearly to scientific stakeholders
• Strong organizational skills and the ability to establish standardized, reproducible data-management practices
• Knowledge of bioanalytical workflows for modalities such as oligonucleotides, proteins, peptides, antibody-drug conjugates, ionizable lipids in lipid nanoparticles, and amino acids

What We Offer You:

We put our employees at the center of everything we do and are committed to providing them, and their families, with benefits that meet their diverse and changing needs. We invest in integrated benefits programs and resources to take care of our employees' physical, mental and emotional, financial and social well-being so they can thrive at home and at work, at any stage of their well-being journey. To learn more about our benefits, visit https://jobs.iqvia.com/benefits. If you're looking to unleash your potential, join IQVIA Laboratories to help make the extraordinary possible! IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries. We create intelligent connections to accelerate the development and commercialization of innovative medical treatments to help improve patient outcomes and population health worldwide. Learn more at https://jobs.iqvia.com

IQVIA is a leading global provider of clinical research services, commercial insights and healthcare intelligence to the life sciences and healthcare industries.

We create connections that accelerate the development and commercialization of innovative medical treatments.

Everything we do is part of a journey to improve patient outcomes and population health worldwide.

To get there, we seek out diverse talent with curious minds and a relentless commitment to innovation and impact.

No matter your role, everyone at IQVIA contributes to our shared goal of helping customers improve the lives of patients everywhere.

Thank you for your interest in growing your career with us.

IQVIA is proud to be an equal opportunity employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, national origin, disability, status as a protected veteran, or any other status protected by applicable law.

https://jobs.iqvia.com/eoe

IQVIA is committed to integrity in our hiring process and maintains a zero tolerance policy for candidate fraud. All information and credentials submitted in your application must be truthful and complete. Any false statements, misrepresentations, or material omissions during the recruitment process will result in immediate disqualification of your application, or termination of employment if discovered later, in accordance with applicable law. We appreciate your honesty and professionalism.

The potential base pay range for this role, when annualized, is $64,200.00 - $133,600.00. The actual base pay offered may vary based on a number of factors including job-related qualifications such as knowledge, skills, education, and experience; location; and/or schedule (full or part-time). Dependent on the position offered, incentive plans, bonuses, and/or other forms of compensation may be offered, in addition to a range of health and welfare and/or other benefits.