Senior Scientist, In Vivo Pharmacology

Bristol Myers Squibb; Cambridge (MA); On-site; USD 88,000 - 122,000; Full time

Job summary

An established industry player is seeking a Senior Scientist in Neuroscience Discovery to drive innovative drug development for neurodegenerative diseases. In this pivotal role, you will leverage your expertise in in vivo pharmacology and collaborate with high-achieving teams to advance groundbreaking therapeutics. This position offers a unique opportunity to contribute to life-changing work that directly impacts patients' lives. Join a diverse and dynamic environment where your talents will be valued, and you can thrive professionally while making a difference in the field of neuroscience.

Benefits

Competitive benefits

Flexible work environment

Career growth opportunities

Supportive culture

Health and wellness programs

Qualifications

• 7+ years experience in academic or industry settings.
• Hands-on experience in in vivo pharmacology and animal handling.
• Experience leading drug discovery programs.

Responsibilities

• Plan and implement studies on BBB delivery technologies.
• Evaluate and select drug candidates using animal models.
• Collaborate with interdisciplinary drug discovery teams.

Skills

In vivo pharmacology

Transgenic animal models

Drug discovery

Biotherapeutics

Genetic medicines

Excellent communication skills

Education

Bachelor's Degree

Master's Degree

Ph.D. in Life Sciences

Tools

AI/ML technologies

Neuroimaging

Job description

1 day ago Be among the first 25 applicants

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Working with Us

Challenging. Meaningful. Life-changing. Those aren't words that are usually associated with a job. But working at Bristol Myers Squibb is anything but usual. Here, uniquely interesting work happens every day, in every department. From optimizing a production line to the latest breakthroughs in cell therapy, this is work that transforms the lives of patients, and the careers of those who do it. You'll get the chance to grow and thrive through opportunities uncommon in scale and scope, alongside high-achieving teams. Take your career farther than you thought possible.

Bristol Myers Squibb recognizes the importance of balance and flexibility in our work environment. We offer a wide variety of competitive benefits, services and programs that provide our employees with the resources to pursue their goals, both at work and in their personal lives. Read more careers.bms.com/working-with-us .

When you join BMS, you are joining a diverse, high-achieving team united by a common mission.

The Neuroscience TRC is committed to the development of transformational therapeutics for patients with neurodegenerative, neuromuscular and neuropsychiatric diseases. A network of internal and external partnerships across neurodegenerative and neuropsychiatric diseases and treatment modalities (small molecules, biologics and genetic medicines) supports our ambition to become leaders in neuroscience. Internal research focuses on causal human biology, matching therapeutic modality to molecular mechanism, and translational discovery enabling a rapid path to clinical proof-of-concept.

Areas of interest include, but are not limited to, the identification of disease modifying and symptomatic therapies for neurodegenerative, neuro-inflammatory neuropsychiatric and neuromuscular diseases; approaches to modulate protein clearance and reduce or eliminate toxic protein production; emerging technologies (RNA, DNA targeting) that when matched to underlying causal human biology may deliver a precision medicine portfolio with a high probability of translational success; AI/ML in target identification drug discovery; neuroimaging and fluid biomarkers to track disease progression and target engagement; novel blood brain-barrier technologies to enhance delivery of biotherapeutics and genetic medicines across the blood-brain barrier.

Here, you'll get the chance to grow and thrive through uncommon opportunities and scope. You'll pursue innovative ideas while advancing professionally alongside some of the brightest minds in biopharma.

Position Summary

The Neuroscience Thematic Research Center (Neuro TRC) leverages external collaborations and internal research to establish a diverse portfolio targeting unmet needs in neurodegenerative, neuropsychiatric, neuroinflammatory and neuromuscular, diseases. The Senior Scientist, Neuroscience Discovery, in collaboration with other members of the Neuroscience TRC, undertakes implementation of in vivo and in vitro studies that enable rapid progression of drug candidates from target identification through clinical proof-of-concept. This position is based in Cambridge, MA, and will join a team of scientists responsible for supporting our collaborative drug discovery mission.

Position Responsibilities

In this laboratory-based role as a Senior Scientist, in vivo Pharmacology, the ideal candidate will

• Plan and implement studies designed to evaluate novel BBB delivery technologies and therapeutic modalities applied to diseases of strategic interest to the Neuroscience TRC
• Maintain transgenic and other animal models to evaluate and select drug candidates for further investment
• Serve as project team member for programs employing novel delivery technologies for neurodegenerative and neuromuscular disorders
  
  

Experience =

Basic Qualifications

• Bachelor's Degree
• 7+ years of academic and / or industry experience

Or

• Master's Degree
• 5+ years of academic and / or industry experience

Or

• Ph.D. or equivalent advanced degree in the Life Sciences
• 2+ of academic and / or industry experience

Preferred Qualifications

• PhD with 4+ years of experience in drug discovery research spanning small molecule, biotherapeutics and genetic medicines discovery, with an emphasis on the evaluation of novel delivery technologies and approaches to enhance CNS delivery of therapeutic agents, using genetically modified animals where appropriate
• Hands on experience in in vivo pharmacology, including small animal handling, surgical techniques, maintenance and breeding of transgenic animal colonies, coordination of research activities and coordination of research activities with external partners and vendors
• Experience working as part of an interdisciplinary drug discovery team
• Experience creating and applying genetically engineered animal models of neurologic disease towards identification of novel therapeutics
• Experience leading drug discovery programs from ideation to delivery of a therapeutic candidate
• Expertise in blood-brain-barrier delivery technologies spanning bi-specific antibodies and genetic medicines
• Experience contributing to external collaborations and partnerships
• Excellent oral and written communication skills
• Ability to work both independently and as an integrated member of multidisciplinary drug development teams
  
  

If you come across a role that intrigues you but doesn't perfectly line up with your resume, we encourage you to apply anyway. You could be one step away from work that will transform your life and career.

Uniquely Interesting Work, Life-changing Careers

With a single vision as inspiring as Transforming patients' lives through science , every BMS employee plays an integral role in work that goes far beyond ordinary. Each of us is empowered to apply our individual talents and unique perspectives in a supportive culture, promoting global participation in clinical trials, while our shared values of passion, innovation, urgency, accountability, inclusion and integrity bring out the highest potential of each of our colleagues.

On-site Protocol

BMS has an occupancy structure that determines where an employee is required to conduct their work. This structure includes site-essential, site-by-design, field-based and remote-by-design jobs. The occupancy type that you are assigned is determined by the nature and responsibilities of your role

Site-essential roles require 100% of shifts onsite at your assigned facility. Site-by-design roles may be eligible for a hybrid work model with at least 50% onsite at your assigned facility. For these roles, onsite presence is considered an essential job function and is critical to collaboration, innovation, productivity, and a positive Company culture. For field-based and remote-by-design roles the ability to physically travel to visit customers, patients or business partners and to attend meetings on behalf of BMS as directed is an essential job function.

BMS is dedicated to ensuring that people with disabilities can excel through a transparent recruitment process, reasonable workplace accommodations/adjustments and ongoing support in their roles. Applicants can request a reasonable workplace accommodation/adjustment prior to accepting a job offer. If you require reasonable accommodations/adjustments in completing this application, or in any part of the recruitment process, direct your inquiries to [e-mail] . Visit careers.bms.com/ eeo -accessibility to access our complete Equal Employment Opportunity statement.

BMS cares about your well-being and the well-being of our staff, customers, patients, and communities. As a result, the Company strongly recommends that all employees be fully vaccinated for Covid-19 and keep up to date with Covid-19 boosters.

BMS will consider for employment qualified applicants with arrest and conviction records, pursuant to applicable laws in your area.

If you live in or expect to work from Los Angeles County if hired for this position, please visit this page for important additional information https //careers.bms.com/california-residents/

Any data processed in connection with role applications will be treated in accordance with applicable data privacy policies and regulations.

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research, Analyst, and Information Technology

• Industries

  Pharmaceutical Manufacturing

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