Experienced Scientist, In-vivo CAR-T

Johnson & Johnson Innovative Medicine; Spring House (PA); On-site; USD 95,000 - 150,000; Full time

Job summary

Johnson & Johnson Innovative Medicine is seeking an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands. The role supports the formulation development of LVV drug products from early to late development, combining hands-on lab work with cross-functional collaboration.

Candidates will have a BS or MS in Life Sciences or Chemical Engineering with 2–4 years of relevant viral vector formulation experience, GxP knowledge, and strong data interpretation

Qualifications

• BS or MS with 2-4 years in Life Sciences or Chemical Engineering is required.
• Experience in formulation development of viral vectors and/or advanced therapies is preferred.
• Hands-on lab experience in drug product development of viral vectors and statistics.
• Understanding of process scale-up, technology transfer, and GxP principles.
• Strong problem-solving and communication skills.

Responsibilities

• Formulate and optimize LVV drug product across development stages.
• Perform hands-on formulation work including design, optimization, and characterization.
• Analyze data to support formulation decisions and development.
• Support formulation robustness activities.
• Contribute to scale-up and manufacturing readiness, including tech transfer.
• Collaborate with Analytical Development, Statistics, API, MSAT, Quality, Manufacturing, and Regulatory teams.
• Document work and results per GxP and data integrity.
• Participate in troubleshooting and continuous improvement.

Skills

Viral vector formulation

Formulation development

GxP compliance

Data interpretation

Cross-functional collaboration

Laboratory experimentation

Process scale-up

Technology transfer

Education

BS/MS in Life Sciences or Chemical Engineering

Job description

At Johnson & Johnson,we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Biotherapeutics R&D

Job Category

Scientific/Technology

All Job Posting Locations

Leiden, Netherlands, Spring House, Pennsylvania, United States of America

Job Description

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal.

Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com.

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

We are searching for the best talent for an Experienced Scientist, In-vivo CAR-T, to be based on-site in Spring House, PA or Leiden, Netherlands.

Purpose

The Experienced Scientist will support the formulation development, optimization, and scale-up of lentiviral vector (LVV) drug product formulation early to late-stage development. The role combines hands‑on laboratory work with strong cross‑functional collaboration to ensure robust, scalable, and GMP‑ready processes.

Key Responsibilities

• Formulation development and optimization of viral vectors e.g., LVV drug product across early and late development stages
• Perform hands‑on laboratory work including formulation design, optimization, and characterization
• Analyze and interpret data to support formulation development, optimization, and decision‑making
• Support formulation robustness activities
• Contribute to scale‑up and manufacturing readiness, including support of technology transfer to internal sites or CMOs
• Collaborate cross‑functionally with Analytical Development, Statistical, API, MSAT, Quality, Manufacturing, and Regulatory teams to ensure alignment on formulation strategy and execution of viral vectors
• Document experimental work and results in accordance with GxP and data integrity requirements
• Participate in troubleshooting activities and continuous process improvement initiatives

Qualifications

Required

• B.S. or M.S. with 2-4 years of experience in an appropriate scientific discipline (Life Sciences or Chemical Engineering) is required
• Relevant experience in formulation development of viral vectors and/or advance therapies
• Strong hands‑on laboratory experience in drug product development of viral vector development and statistics
• Understanding of process scale‑up, technology transfer, and GxP principles
• Strong scientific problem‑solving and data interpretation skills
• Hands‑on, proactive, and detail‑oriented approach
• Ability to work effectively in a cross‑functional, matrixed environment
• Clear and concise communication skills (written and verbal)
• Ability to manage multiple priorities in a dynamic development environment

Preferred

• Experience with viral vector platforms, LVV in particular, and/or advanced therapies
• Familiarity with formulation implementation for both early and late‑stage development, process validation (e.g., LCPV) and manufacturing support
• Exposure to both early and late‑stage development requirements or commercial readiness activities

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation, gender identity, age, national origin, disability, protected veteran status or other characteristics protected by federal, state or local law. We actively seek qualified candidates who are protected veterans and individuals with disabilities as defined under VEVRAA and Section 503 of the Rehabilitation Act.

Johnson and Johnson is committed to providing an interview process that is inclusive of our applicants’ needs. If you are an individual with a disability and would like to request an accommodation, please email the Employee Health Support Center ([e-mail]) or contact AskGS to be directed to your accommodation resource.

Required Skills

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression

Preferred Skills

Analytical Reasoning, Biochemistry, Chemistry, Manufacturing and Control (CMC), Coaching, Collaboration, Conducting Experiments, Data Quality, Drug Discovery Development, Molecular Diagnostics, Patent Applications, Pharmacogenetics, Report Writing, Research Documents, Scientific Research, Technologically Savvy, Written Expression