Senior Scientist - Immunology

Enigma Search; Redwood City (CA); On-site; USD 130,000 - 165,000; Full time

Job summary

A well-funded biotech startup in Redwood City is seeking a highly motivated scientist to join its drug discovery team. The role focuses on early-stage discovery efforts for autoimmune and inflammatory diseases, requiring expertise in in vitro pharmacology and a strong understanding of disease biology.

Benefits

Competitive compensation

Equity

401(k) matching

Comprehensive healthcare benefits

Qualifications

• Ph.D. or M.S. in relevant field required.
• Strong understanding of drug target validation and early drug development.
• Experience with biologics platforms preferred.

Responsibilities

• Design and execute in vitro pharmacology studies.
• Develop assays using reporter systems and primary cells.
• Support in vivo pharmacology studies.

Skills

In vitro pharmacology

Gene delivery systems

Human primary cell models

In vivo animal models

Drug target validation

Excellent communication skills

Education

Ph.D. or M.S. in Immunology, Cell Biology, Pharmacology, or related field

Job description

Get AI-powered advice on this job and more exclusive features.

This range is provided by Enigma Search . Your actual pay will be based on your skills and experience — talk with your recruiter to learn more.

Base pay range

$130,000.00/yr - $165,000.00/yr

Summary

A well-funded biotech startup founded by experienced entrepreneurs with a strong track record in biologics is focused on discovering and developing differentiated biologic therapies for immunological and other complex diseases. Backed by a seasoned leadership team known for advancing innovative biologics to global markets, the company is driven by a passion for science, collaboration, and improving patient outcomes. Headquartered in Redwood City, CA, the company offers competitive compensation, equity, 401(k) matching, and comprehensive healthcare benefits.

We are seeking a highly motivated scientist to join our multidisciplinary drug discovery team. This individual will play a key role in driving early-stage discovery efforts focused on autoimmune, inflammatory, and metabolic diseases. The ideal candidate will bring strong technical expertise in in vitro pharmacology, gene delivery systems, human primary cell models, and in vivo animal models, paired with a deep understanding of disease biology and translational relevance. This position offers the opportunity to contribute across multiple programs and therapeutic platforms in a dynamic, collaborative biotech environment.

Key Responsibilities

• Design, execute, and interpret in vitro pharmacology studies to assess novel therapeutic candidates
• Develop and refine assays using reporter systems, primary cells, and engineered cell lines
• Generate and apply lentiviral and retroviral vectors for gene expression and genome editing
• Conduct functional studies in human primary immune and stromal cells (e.g., PBMCs, fibroblasts, hepatocytes)
• Support in vivo pharmacology studies, including model selection, dosing, sample collection, and biomarker analysis
• Collaborate with cross-functional teams to advance programs from target validation through lead optimization
• Maintain detailed experimental records and clearly present findings in team meetings

Qualifications

• Ph.D. or M.S. in Immunology, Cell Biology, Pharmacology, or a related field
• Strong understanding of drug target validation and early drug development
• Experience with biologics platforms preferred, including canonical and engineered antibodies, bi-specifics, Fc-fusion proteins, and novel scaffolds
• In-depth scientific knowledge in immunology, with emphasis on autoimmunity and inflammation strongly preferred
• Familiarity with mouse models, including handling, dosing, tissue collection, and biomarker analysis
• Excellent written and verbal communication skills

Seniority level

• Seniority level

  Mid-Senior level

Employment type

• Employment type

  Full-time

Job function

• Job function

  Research

Referrals increase your chances of interviewing at Enigma Search by 2x

Get notified about new Research And Development Specialist jobs in Redwood City, CA.

Research Associate (I-II-III) - Application Development

Junior or Assistant Research Specialist - Fattahi Lab

Research Associate, Analytical Development (CONTRACT Position)

Research And Development Scientist, Food Product / Process Developer

Principal Research Scientist I/II, CMC Purification Development

Sr. Research Associate - Product Development

Research Associate (Product Development)

Research Associate, Analytical Development

Analytical Development Research Associate II

Research Associate I, Pharmaceutical Development (Contactor)

Junior, Assistant, Associate, or Full Specialist – He Lab

Research Associate II (NGS Assay Development)

Analytical Development Research Associate III

Process Integration Technologist, R&D Engineering

R&D Associate / Scientist – Protein Expression and Purification

Research and Development Technical Services Specialist

Research Scientist - Electron Beam Source Development

Milpitas, CA $130,400.00-$221,700.00 1 week ago

Research and Development (R&D) Optical Integration Engineer

San Ramon, CA $137,000.00-$169,000.00 8 months ago

Research Associate, Analytical Development I

We’re unlocking community knowledge in a new way. Experts add insights directly into each article, started with the help of AI.