Senior Scientist II, Ex Vivo Electrophysiology

Heart Failure Society of America; Cambridge (MA); On-site; USD 100,000 - 150,000; Full time

Job summary

A leading company in the field of psychiatry drug discovery is seeking an electrophysiologist to work on cutting-edge research. You will contribute to understanding synaptic dysfunction and develop experimental methodologies that drive innovative solutions. The role offers the chance to work collaboratively within a dynamic team, influencing future discoveries in treatment.

Benefits

Comprehensive benefits package including paid time off

Medical, dental, and vision insurance

401(k) eligibility

Participation in short-term and long-term incentive programs

Qualifications

• Typically requires 4+ years (PhD), 10+ years (MS), or 12+ years (BS).
• Experience in slice electrophysiology for intact circuitry.
• Proficient in hypothesis-driven studies.

Responsibilities

• Execute and communicate original technical ideas.
• Drive electrophysiology experiments to investigate synaptic function.
• Present findings to internal teams and contribute to strategic decisions.

Skills

Whole-cell patch-clamp electrophysiology

Data processing and interpretation

Collaboration in cross-functional teams

Education

PhD in neuroscience

MS in neuroscience

BS in neuroscience

Job description

ICompany Description

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas - immunology, oncology, neuroscience, and eye care - and products and services in our Allergan Aesthetics portfolio. For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and Tik Tok.

Job Description

AbbVie is seeking an experienced and highly motivated electrophysiologist to join our Circuit Biology team within Discovery Psychiatry. This pivotal role involves facilitating in vitro and ex vivo electrophysiological insights of circuit biology to drive our understanding of synaptic and circuit dysfunction in psychiatric disorders and treatment. This is an excellent opportunity to work at the forefront of psychiatry drug discovery research, contributing to target validation and compound profiling studies within a dynamic and collaborative team.

Key Responsibilities

• Independently conceive, execute, and communicate original technical ideas and novel multi-disciplinary research that achieves project and area goals
• Drive internal electrophysiology efforts by developing and optimizing disease-relevant in vitro and ex-vivo experiments to investigate synaptic and circuit function
• Develop and maintain slice electrophysiology technology, methodology, and utility in psychiatric drug discovery
• Generate, through lab-based activities, slice electrophysiology data to support projects
• Ensure alignment of electrophysiology efforts with the broader goals of cross-functional teams
• Present findings to internal teams and external collaborators or conferences
• Contribute to strategic decision-making in psychiatry drug discovery
• Provide scientific guidance and training to junior scientists and research associates
• Serve as a lead scientist on projects and contribute scientific insights across multiple other project teams

Qualifications

• PhD, MS, or BS in neuroscience, or related field, with typically 4+ (PhD), 10+ (MS) or 12+ (BS) years of experience
• Extensive experience in whole-cell patch-clamp electrophysiology in acute brain slices, in vitro and ex vivo slice electrophysiology
• Extensive experience using slice electrophysiology to study intact circuitry from striatal, cortical and hippocampal networks
• Demonstrated expertise in the design and execution of hypothesis-driven studies related to synaptic and circuit function
• Ability to process and interpret large datasets using appropriate software tools
• Strong ability to work in cross-functional teams and effectively communicate scientific findings

Desired Qualifications

• Previous industry experience within early discovery, preferably within psychiatry research
• Expertise in ion channel drug discovery
• Recognized and sought out as an expert in field or discipline
• Track record of impactful publications

Additional Information

Applicable only to applicants applying to a position in any location with pay disclosure requirements under state or local law:

• The compensation range described below is the range of possible base pay compensation that the Company believes in good faith it will pay for this role at the time of this posting based on the job grade for this position. Individual compensation paid within this range will depend on many factors including geographic location, and we may ultimately pay more or less than the posted range. This range may be modified in the future.
• We offer a comprehensive package of benefits including paid time off (vacation, holidays, sick), medical/dental/vision insurance and 401(k) to eligible employees.
• This job is eligible to participate in our short-term incentive programs.
• This job is eligible to participate in our long-term incentive programs.

Note: No amount of pay is considered to be wages or compensation until such amount is earned, vested, and determinable. The amount and availability of any bonus, commission, incentive, benefits, or any other form of compensation and benefits that are allocable to a particular employee remains in the Company's sole and absolute discretion unless and until paid and may be modified at the Company's sole and absolute discretion, consistent with applicable law.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

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https://www.abbvie.com/join-us/reasonable-accommodations.htmlI