Senior Scientist I, Translational Research

Tempus; Chicago (IL); On-site; USD 110,000 - 175,000; Full time

Job summary

Tempus, a Chicago-based company, leverages a real-world evidence platform to deliver real-time insights for precision medicine. We partner with pharma to advance oncology drug development, applying multimodal analyses to inform clinical programs and guide decisions.

The role requires a PhD in a quantitative field or equivalent, 4+ years in drug development with genomic data, and proficiency in R/Python. Travel ~25% and collaboration across Research, Engineering and Data Science are expected.

Qualifications

• PhD required in a quantitative science or equivalent with strong computational biology background.
• Minimum 4+ years in drug development using genomic and multimodal data.
• Proficient in R, Python, and SQL with experience in multi-omics integration.
• Experience communicating insights to non-technical stakeholders.
• Familiar with cloud computing (AWS) and containerization (Docker).

Responsibilities

• Partner with pharma clients to design and execute computational research projects.
• Analyze and integrate large clinical and molecular datasets to extract insights.
• Stay ahead of oncology drug development trends and identify new markets.
• Co-architect solutions with clients and maintain R&D relationships.
• Author whitepapers on multimodal analysis and AI in drug discovery.
• Collaborate with Product and Engineering to streamline analyses.
• Track progress against strategic objectives with leadership.
• Travel ~25% domestically and internationally.

Skills

R

Python

SQL

Pandas

NumPy

SciPy

Scikit-learn

Jupyter Notebooks

RStudio

tidyverse

ggplot

Git

Docker

AWS

HTML5

CSS3

JavaScript

D3

Plotly

Flask

Dask

Education

PhD in Biostatistics/Statistical Genetics, Cancer Genetics, Bioinformatics, Computational Biology, Computational Immunology or similar

PhD in Molecular Biology or Immunology with strong computational biology background

Tools

Plotly

D3

Flask

Dask

Job description

Passionate about precision medicine and advancing the healthcare industry?Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time.Responsibilities: Partner with our pharma clients to design, develop and execute computational research projects leveraging the Tempus platform to advance precision medicine research programs. Analyze and integrate large diverse clinical and molecular datasets to extract insights and drive new research opportunities. Stay ahead of research and industry trends in oncology drug development, and identify specific areas where the Tempus platform can establish new markets. Become an expert in our biopharma partners’ strategy, pipeline and portfolio to proactively determine all areas that the Tempus platform could add value to the drug development process of our partners. Develop and drive global account strategy in coordination with the account team. Document, summarize and communicate highly technical results and methods clearly to non-technical audiences. Work directly with clients to co-architect solutions and projects that leverage the Tempus platform to solve customers' challenges and maintain R&D relationships as the trusted technical advisor. Author whitepapers and illustrate the value of multimodal analysis and AI in drug discovery in coordination with our Research, Engineering & Data Science teams. Work with Product and Engineering teams to streamline workflow of computational analyze Contribute to the development of the portfolio by providing feedback to leadership regarding client responses and suggestions; maintain a solution-oriented mindset. Track progress against defined strategic objectives and goals; review progress/setbacks frequently wi broader Account Team and Tempus leadership. Travel approximately 25% of working time, domestically and internationally. Preferred Qualification PhD degree in a quantitative discipline (e.g. Biostatistics/Statistical Genetics, Cancer Genetics, Bioinformatics, Computational Biology, Computational Immunology or similar). Alternatively, a PhD in Molecular Biology or Immunology combined with a very strong record of computational biology. Minimum 4+ years in drug development leveraging genomic and multimodal data for drug discovery and development . Strong understanding of molecular data and artificial intelligence in drug discovery with experience integrative modeling of multi-modal clinical and omics data. Proficient in R, Python, and SQ Previous experience working with large transcriptome data sets. Strong understanding of Cancer, Immunology, Clinical Trials and Real World Evidence Platforms . Prior consulting and/or client facing experience is highly desirable Thrive in a fast-paced environment and willing to shift priorities seamlessly.Preferred Experience: Proven track record of developing solutions utilizing molecular and multimodal data. Demonstrated ability to influence without authority (both with internal and external stakeholders Proactive mindset that bridges ideas to implementable solutions, and can help move both internal and external stakeholders to quickly solve problems Experience with communicating insights and presenting concepts to diverse audiences. Strong peer-reviewed publication record. Experience with: Pandas, NumPy, SciPy, Scikit-learn, Jupyter Notebooks, RStudio, tidyverse, ggplot, Git, matplotlib, seaborn, HTML5, CSS3, JavaScript, D3, Plot.ly, Flask, Dask, Docker, AWS. Team player mindset and ability to work in an interdisciplinary team. Goal orientation, self motivation, and drive to make a positive impact in healthcare.CHI: $100,000-$160,000 NYC/SF: $115,000-$175,000The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience. Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.About UsTempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics.We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives.Why Work Here?We’re looking for people who can change the world.Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.