Director, Strategy & Operations

Tempus AI, Inc.; Chicago (IL); Hybrid; USD 150,000 - 220,000; Full time

Benefits offered by this job

Incentive compensation

RSUs

Medical benefits

Job summary

Tempus AI, Inc. is seeking a strategic operator to sit at the center of the commercial org, turning strategy into repeatable practice.

You will own enablement, tools, and operating rhythms that let the sales team win consistently across launches, trainings, and field execution. In this high-ownership role, you’ll drive go-to-market framework for new data and software offerings, build a scalable enablement engine, and lead a persona-based approach to field engagement with Medical Affairs and

Qualifications

• 8+ years in commercial strategy, sales operations, enablement, revenue operations, or chief-of-staff roles.
• A track record of building repeatable commercial systems (enablement, GTM launches, sales ops infrastructure).
• Strong cross-functional orchestration; comfortable aligning marketing, pricing, sales, and data without formal authority.

Responsibilities

• Launch go-to-market strategy for new data/software offerings end-to-end.
• Build a comprehensive training curriculum and enablement function from the ground up.
• Design the operating backbone that enables scalable commercial engine with metrics and cadences.
• Lead the GTM transformation to a use-case / persona-led motion with senior leaders.
• Elevate the selling motion by focusing on solutions rather than SKUs.
• Diagnose deal bottlenecks and institute fixes to shorten time-to-close.

Skills

Commercial strategy

Sales operations

Enablement

Revenue operations

Cross-functional orchestration

Job description

Passionate about precision medicine and advancing the healthcare industry? Recent advancements in underlying technology have finally made it possible for AI to impact clinical care in a meaningful way. Tempus' proprietary platform connects an entire ecosystem of real-world evidence to deliver real-time, actionable insights to physicians, providing critical information about the right treatments for the right patients, at the right time. Tempus's Data & AI Partnerships business is scaling fast, and how we sell needs to scale with it. This role is the connective tissue that turns commercial strategy into repeatable practice: part strategist, part operator, part quarterback. You will sit at the center of the commercial org, building the enablement, tools, and operating rhythms that let a growing sales team win consistently. It is a high-ownership, high-visibility role for someone who can move from executive leadership strategy to the details of a launch plan or a rep's deal prep, driving outcomes across teams without needing formal direct authority.

What you'll own

• Quarterback new offering launches Drive go-to-market strategy for new data and software offerings end-to-end: establish launch frameworks, commercial rhythms, and orchestrate Sales, Marketing, Product, and Data into one aligned motion to ensure seamless market execution.
• Sales training & enablement Build a comprehensive training curriculum and enablement function from the ground up: onboarding, ongoing skill-building, deal playbooks, and persona-based positioning to drive field effectiveness.
• Build a scalable commercial engine Design the operating backbone that lets the commercial team grow without losing rigor: the tools, AI-powered dashboards, and practices that turn individual talent into a repeatable system. Define the metrics, cadences, and infrastructure that make performance visible and coachable.
• Lead the GTM transformation to a use-case / persona-led motion Re-architect field execution by tailoring messaging, content, and discovery frameworks to specific buyer personas (for example, Medical Affairs versus Clinical Development). Partner with senior commercial, data, and operations leaders to bring this segmented approach to life in the field.
• Elevate the selling motion: solutions, not SKUs Sharpen how the team engages customers: clarifying the key “asset battles,” grounding conversations in real customer problems and how Tempus uniquely solves them, and coaching the team to architect client solutions rather than pitch products.
• Accelerate deal velocity and remove friction Diagnose systemic deal bottlenecks across the sales cycle and institute operational fixes to streamline approvals, clear commercial barriers, and shorten time-to-close.

What Success Looks Like (First 6 to 12 Months)

• A functioning enablement engine (curriculum, playbooks, and tooling) that measurably shortens rep onboarding ramp and lifts field effectiveness.
• Measurable improvement in sales velocity across priority buyer personas, including reduced proposal-to-close timelines.
• At least one new strategic offering launched successfully end-to-end on a clear, repeatable GTM playbook.
• Field adoption of AI-driven commercial tools and dashboards integrated into standard weekly operating cadences.

Base Qualifications

• 8+ years in commercial strategy, sales operations, enablement, revenue operations, or chief-of-staff roles.
• A track record of building repeatable commercial systems (enablement, GTM launches, sales ops infrastructure), not just running one-off projects.
• Strong cross-functional orchestration; comfortable aligning marketing, pricing, sales, and data without formal authority over them.
• Fluency moving between strategy and execution, and between executive leadership and the field.
• Analytical rigor and comfort with commercial tooling, dashboards, and sales pipeline analytics.
• A structured, self-directed operator who brings order to ambiguity and drives outcomes across teams.

Preferred Qualifications

• Experience in life sciences, healthcare, health tech, or data-focused SaaS.
• Direct experience applying AI tools or automated workflows to sales and commercial operations.
• Familiarity with the use of real-world data (RWD) in life sciences or clinical research settings.

$150,000 - $220,000 #LI-NK1 #LI-HYBRID The expected salary range above is applicable if the role is performed from California and may vary for other locations (Colorado, Illinois, New York). Actual salary may vary based on qualifications and experience.

Tempus offers a full range of benefits, which may include incentive compensation, restricted stock units, medical and other benefits depending on the position.

Additionally, for remote roles open to individuals in unincorporated Los Angeles – including remote roles- Tempus reasonably believes that criminal history may have a direct, adverse and negative relationship on the following job duties, potentially resulting in the withdrawal of the conditional offer of employment: engaging positively with customers and other employees; accessing confidential information, including intellectual property, trade secrets, and protected health information; and appropriately handling such information in accordance with legal and ethical standards. Qualified applicants with arrest or conviction records will be considered for employment in accordance with applicable law, including the Los Angeles County Fair Chance Ordinance for Employers and the California Fair Chance Act.

We are an equal opportunity employer. We do not discriminate on the basis of race, religion, color, national origin, gender, sexual orientation, age, marital status, veteran status, or disability status.

Tempus was founded in August of 2015 by Eric Lefkofsky, after his wife was diagnosed with Breast Cancer. Shortly after he founded the company in an effort to bring the power of technology and artificial intelligence to cancer care, he convinced Ryan Fukushima to join as the company’s first employee. Ryan and Eric began assembling a world class team, focused on building the first version of a platform capable of ingesting real time healthcare data in an effort to personalize diagnostics. We built the platform for oncology and have expanded it to neuropsychiatry, cardiology, infectious disease (through COVID), and radiology. Despite our rapid growth, our mission remains the same—to help make sure patients are on the right drug at the right time, so they can live longer and healthier lives. We’re looking for people who can change the world. Who question the status quo and don’t shy away from tough problems. For the builders who are never done building and the learners who are never done learning. We’re looking for passionate people with undying curiosity. Those who want to attack one of the most challenging problems mankind has ever faced. Head on.