Senior Scientist I (Analytical Chemistry)

Exelixis, Inc.; Alameda (CA); On-site; USD 116,000 - 166,000; Full time

Job summary

An established industry player in the biotech sector is seeking a Senior Scientist I in Analytical Chemistry. This role involves leading small molecule separation and characterization activities using advanced chromatography tools. You will manage external vendors and enhance analytical workflows, contributing to innovative drug discovery projects. Join a team dedicated to making a difference in cancer treatment, where your expertise will help shape the future of medicine. The company offers a supportive environment with comprehensive benefits and opportunities for professional growth, making it a perfect place for passionate scientists to thrive.

Benefits

401k plan with company contributions

Medical, dental, and vision coverage

Life and disability insurance

Flexible spending accounts

Discretionary annual bonus program

Opportunity to purchase company stock

15 accrued vacation days

17 paid holidays

10 sick days

Qualifications

• Ph.D. or equivalent in analytical chemistry with relevant chromatography experience.
• Strong knowledge of chromatography techniques and instrumentation.

Responsibilities

• Perform high throughput purification and analysis of small molecule compounds.
• Manage external vendors for laboratory instrument maintenance and optimization.

Skills

Chromatography

Data Analysis

Problem Solving

Interpersonal Skills

Communication Skills

Education

Ph.D. in Analytical Chemistry

MS in Analytical Chemistry

BS in Analytical Chemistry

Tools

LCMS

HPLC

UPLC

SFC

Automated Liquid Handlers

Job description

Senior Scientist I (Analytical Chemistry)

Apply locations Alameda, CA

time type Full time

posted on Posted 2 Days Ago

job requisition id JR6074

SUMMARY/JOB PURPOSE:

The successful candidate will be responsible for day-to-day small molecule separation, separation and characterization activities using industry-leading chromatography tools for research and development projects. The successful candidate will also be responsible for managing external vendors and service providers for laboratory instrument maintenance, troubleshooting and technical/process development to optimize analytical workflow efficiency and throughput.

ESSENTIAL DUTIES AND RESPONSIBILITIES:

• Perform high throughput compound library purification using LCMS detection and automation software.
• Perform separation, purification, analysis and scale up purification of small molecule compounds from medicinal chemistry synthesis including chiral separation.
• Use chromatographic methods including HPLC/UPLC, LCMS and SFC to separate compounds with complex matrices (problem solving).
• Ability to use automated liquid handler robots to perform sample preparation pre and post purification.
• Perform data analysis and prepare analysis report under supervision.
• Participate in group, project team and departmental research meetings.
• Maintain laboratory notebooks in accordance with company policies and practices.
• Comply with safe laboratory practices and EH&S guidelines.

SUPERVISORY RESPONSIBILITIES:

• No supervisory responsibilities.

EDUCATION/EXPERIENCE/KNOWLEDGE & SKILLS:

• Ph.D. in analytical chemistry or related discipline with zero or more years of chromatography experience related to drug discovery; or,
• MS in analytical chemistry or related discipline and a minimum of five years of chromatography experience related to drug discovery; or,
• BS in analytical chemistry or related discipline and a minimum of seven years of chromatography experience related to drug discovery; or,
• Equivalent combination of education and experience.

Experience (desired):

• Experience using LCMS, UPLC and SFC in drug discovery setting
• Experience with purification and characterization of small molecule compounds
• Experience with automation for liquid handling processes

Knowledge/Skills:

• Knowledge of automatic liquid handler/Robotics and related data processing software
• Strong knowledge of small molecule separation by modern chromatographic techniques such as Reverse Phase LC/UPLC, LCMS and SFC.
• Strong knowledge of LC, LCMS and SFC instrumentation
• Good interpersonal skills, flexibility and works well within a team environment
• Excellent written and verbal communication skills

WORKING CONDITIONS:

Discovery/Alameda:

• Environment: primarily working in laboratories or in office
• Travel as required (to be less than 10%)

COMPENSATION:

Our compensation reflects the cost of labor across several U.S. geographic markets, and we pay differently based on those defined markets. The base pay range for this position is $116,000 - $165,500 annually. The base pay range may take into account the candidate’s geographic region, which will adjust the pay depending on the specific work location. The base pay offered will take into account the candidate’s geographic region, job-related knowledge, skills, experience and internal equity, among other factors.

In addition to the base salary, as part of our Total Rewards program, Exelixis offers a comprehensive employee benefits package, including a 401k plan with generous company contributions, group medical, dental and vision coverage, life and disability insurance, and flexible spending accounts. Employees are also eligible for a discretionary annual bonus program, or if field sales staff, a sales-based incentive plan. Exelixis also offers employees the opportunity to purchase company stock, and receive long-term incentives, 15 accrued vacation days in their first year, 17 paid holidays including a company-wide winter shutdown in December, and up to 10 sick days throughout the calendar year.

DISCLAIMER:
The preceding job description has been designed to indicate the general nature and level of work performed by employees within this classification. It is not designed to contain or be interpreted as a comprehensive inventory of all duties, responsibilities and qualifications required of employees assigned to the job.

We are an Equal Opportunity Employer and do not discriminate against any employee or applicant for employment because of race, color, sex, age, national origin, religion, sexual orientation, gender identity, status as a veteran, and basis of disability or any other federal, state or local protected class.

About Us

Every Exelixis employee is united in an ambitious cause: to launch innovative medicines that give patients and their families hope for the future. In this pursuit, we know our employees are our most valuable asset. After operating in the challenging biotech sector for 25 years, we have a proven track record of resiliency in the face of adversity. The success of our lead product has provided a solid commercial foundation allowing us to reinvigorate our research efforts, and grow our team in areas such as Drug Discovery, Clinical Development and Commercial.

As we expand our global partnerships and further reinvest in R&D to help us discover the next breakthrough for difficult-to-treat cancers, we’re seeking to add talented, dedicated employees to power our mission.

Cancer is our cause. Make it yours, too.