Senior Scientist Discovery, Immunology

Johnson Johnson; San Diego (CA); On-site; USD 120,000 - 180,000; Full time

Benefits offered by this job

401(k) plan

Pension/retirement program

Long-term incentive program

Job summary

Johnson & Johnson is seeking a Senior Scientist to join the Discovery Immunology group in La Jolla, CA. The role focuses on advancing therapeutics for autoimmune diseases through target validation and program progression in a lab-based setting.

You will design and execute complex immunology studies, mentor colleagues, and collaborate across functions to influence program decisions and drive publication-ready results.

Qualifications

• Ph.D. in Immunology or a related field with 1-3 years of additional relevant laboratory experience.
• Strong foundation in immunology, including an understanding of the cells, cytokines, and signaling pathways that drive autoimmune disease.
• Demonstrated hands-on experience in primary cell isolation and cell culture, in vitro cell-based models of inflammation, in vivo models of autoimmune disease, and spectral flow cytometry.
• Ability to leverage multi-omic approaches such as single cell RNASeq and spatial transcriptomics to explore novel biology and the MoA of therapeutic candidates.
• Strong scientific judgment, excellent written and oral communication skills, and ability to work effectively in a highly matrixed environment.

Responsibilities

• Independently design, execute, analyze, and interpret complex biological studies that inform target validation, mechanism of action, and program progression.
• Own the scientific quality, timely delivery, and documentation of research results.
• Synthesize literature and data, communicate clear recommendations, and influence decisions with project teams and management.
• Provide technical guidance and scientific mentorship to colleagues; partner across functions to advance program objectives.
• Contribute, as appropriate, to abstracts/posters, publications, technical reports, and patent applications.

Skills

Immunology

Primary cell isolation

Cell culture

In vivo models

Single-cell RNA-Seq

Spatial transcriptomics

Spectral flow cytometry

Scientific mentoring

Literature synthesis

Cross-functional collaboration

Education

Ph.D. in Immunology

Tools

Spectral flow cytometry

Single-cell RNA-Seq

Spatial transcriptomics

Job description

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Biological Research

Job Category

Scientific/Technology

All Job Posting Locations

San Diego, California, United States of America

Job Description

About Innovative Medicine

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow.

Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases.

Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

Learn more at https://www.jnj.com/innovative-medicine

We are searching for the best talent for a Senior Scientist to join the Discovery Immunology group to help advance innovative therapeutics for autoimmune diseases in La Jolla, CA. This lab-based role offers the opportunity to shape discovery strategy and influence program decisions from target validation through drug candidate progression.

Responsibilities

• Independently design, execute, analyze, and interpret complex biological studies that inform target validation, mechanism of action, and program progression.
• Own the scientific quality, timely delivery, and documentation of research results.
• Synthesize literature and data, communicate clear recommendations, and influence decisions with project teams and management.
• Provide technical guidance and scientific mentorship to colleagues; partner across functions to advance program objectives.
• Contribute, as appropriate, to abstracts/posters, publications, technical reports, and patent applications.

Required qualifications

• Ph.D. in Immunology or a related field with 1-3 years of additional relevant laboratory experience.
• Strong foundation in immunology, including an understanding of the cells, cytokines, and signaling pathways that drive autoimmune disease.
• Demonstrated hands-on experience in primary cell isolation and cell culture, in vitro cell-based models of inflammation, in vivo models of autoimmune disease, and spectral flow cytometry.
• Ability to leverage multi-omic approaches such as single cell RNASeq and spatial transcriptomics to explore novel biology and the MoA of therapeutic candidates.
• Strong scientific judgment, excellent written and oral communication skills, and ability to work effectively in a highly matrixed environment.

Preferred qualifications

• Experience performing in vitro cell-based assays to measure the potency of large or small molecule therapeutics.
• Experience with laboratory automation to increase experimental scale and efficiency.

Subject to the terms of their respective plans, employees are eligible to participate in the Company's consolidated retirement plan (pension) and savings plan (401(k)).

This position is eligible to participate in the Company's long-term incentive program.

Subject to the terms of their respective policies and date of hire, employees are eligible for the following time off benefits

• Vacation -120 hours per calendar year
• Sick time - 40 hours per calendar year; for employees who reside in the State of Colorado -48 hours per calendar year; for employees who reside in the State of Washington -56 hours per calendar year
• Holiday pay, including Floating Holidays -13 days per calendar year
• Work, Personal and Family Time - up to 40 hours per calendar year
• Parental Leave - 480 hours within one year of the birth/adoption/foster care of a child
• Bereavement Leave - 240 hours for an immediate family member: 40 hours for an extended family member per calendar year
• Caregiver Leave - 80 hours in a 52-week rolling period10 days
• Volunteer Leave - 32 hours per calendar year
• Military Sp