Scientist, Discovery Immunology

Johnson Johnson; Spring House (PA); Sur place; USD 110 000 - 170 000; Plein temps

Résumé du poste

Johnson & Johnson is seeking a Scientist Discovery Immunology in Spring House, PA. You will establish experimental proof of concept for novel immunology pathways, translating human datasets and literature into focused bench studies.

The role involves developing in vitro and co-culture models, testing mechanistic hypotheses, and sharing insights with interdisciplinary teams to drive therapeutic opportunities.

Qualifications

• BS or MS in Immunology, Cell Biology, or related field.
• Experience in autoimmune/autoinflammatory disease research beneficial.
• Ability to integrate literature with experimental data to test hypotheses.

Responsabilités

• Establish proof-of-concept for novel pathways in immunology.
• Translate insights from datasets and literature into bench studies.
• Develop in vitro and co-culture models to test hypotheses.
• Communicate results to multidisciplinary teams and guide research direction.

Connaissances

Immunology

Cell Biology

Myeloid biology

Literature integration

Single-cell omics

Collaboration

Attention to detail

Formation

BS or MS in Immunology/Cell Biology

Outils

Flow cytometry

Co-culture models

qPCR

Transcriptomics

CRISPR perturbation

Lentiviral transduction

Description du poste

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow, and profoundly impact health for humanity. Learn more at jnj.com .

As guided by Our Credo, Johnson & Johnson is responsible to our employees who work with us throughout the world. We provide an inclusive work environment where each person is considered as an individual. At Johnson & Johnson, we respect the diversity and dignity of our employees and recognize their merit.

Job Function

Discovery & Pre-Clinical/Clinical Development

Job Sub Function

Biological Research

Job Category

Scientific/Technology

All Job Posting Locations

Spring House, Pennsylvania, United States of America

Job Description

Scientist Discovery Immunology

About Innovative Medicine

At Johnson & Johnson, we believe health is everything. Our strength in healthcare innovation empowers us to build a world where complex diseases are prevented, treated, and cured, where treatments are smarter and less invasive, and solutions are personal. Through our expertise in Innovative Medicine and MedTech, we are uniquely positioned to innovate across the full spectrum of healthcare solutions today to deliver the breakthroughs of tomorrow and profoundly impact health for humanity. Learn more at https://www.jnj.com/ .

About Immunology

Our expertise in Innovative Medicine is informed and inspired by patients, whose insights fuel our science-based advancements. Visionaries like you work on teams that save lives by developing the medicines of tomorrow. Our Immunology team leads in the development of transformational medicines for immunological disorders and illnesses. You can influence where medicine is going by restoring health to millions of people living with immune diseases. Join us in developing treatments, finding cures, and pioneering the path from lab to life while championing patients every step of the way.

We are seeking an innovative, scientifically curious bench scientist to join our team in Spring House, PA.

This scientist will establish experimental proof of concept for novel biological pathways in emerging areas of immunology, enabling JJIM to advance impactful new therapies for people with autoimmune and autoinflammatory diseases.

The successful candidate will translate insights from proprietary human datasets, published literature, and computational analyses into focused, hands‑on bench studies. They will develop disease‑relevant in vitro and co‑culture models; design, execute, and interpret experiments that test key mechanistic hypotheses; and generate rigorous proof‑of‑concept data to validate emerging pathways and therapeutic opportunities. Working across multidisciplinary teams, they will use experimental findings to refine research direction and clearly communicate recommendations that support progression of the most compelling biology.

Qualifications

• B.S. or M.S. in Immunology, Cell Biology, or a related discipline, with relevant academic or industry research experience.
• Strong foundation in myeloid, stromal, and mucosal biology and familiarity with how these compartments contribute to chronic inflammation, tissue damage, and healing in immune‑mediated diseases affecting the gut, joint, lung, and skin.
• Ability to integrate literature, multidimensional biological data, and experimental findings to generate and independently test mechanistic hypotheses.
• Familiarity with single‑cell, bulk omics, and spatial transcriptomic datasets and their application to experimental design.
• A proven track record demonstrating clear scientific communication and effective multidisciplinary collaboration
• Self‑motivated, proactive, strong attention to detail

Technical Skills & Experimental Expertise

• Culture, manipulation, isolation, and functional characterization of human cell lines and primary immune or tissue‑derived cells.
• Development and optimization of physiologically relevant and fit‑for‑purpose in vitro, co‑culture, and ex vivo models for human disease biology.
• Multiparameter flow cytometry, imaging‑based assays, and analysis of cellular phenotype, function, and cell‑cell interactions.
• Protein and gene‑expression analysis using ELISA, multiplex cytokine assays, qPCR, and transcriptomic approaches.
• Familiarity with cell‑engineering methods, including lentiviral transduction, siRNA, and CRISPR‑based perturbation.
• Familiarity with organ‑on‑a‑chip and micro‑fluidics‑based culture systems for primary cells is preferred

Johnson & Johnson is an Equal Opportunity Employer. All qualified applicants will receive consideration for employment without regard to race, color, religion, sex, sexual orientation