Senior Scientist, Chemical Development — GMP Scale-Up

Vividion; San Diego (CA); Híbrido; USD 165 000 - 185 000; Tempo integral

Resumo da oferta

Vividion Therapeutics, Inc. in San Diego seeks a Principal Scientist, Chemical Development to build robust synthetic routes and deliver non-GMP & GMP material on multi-kilogram scale.

You will lead external scientists, coordinate with CDMO partners, and drive API development from preclinical to proof-of-concept across programs. You will collaborate with QA and regulatory teams, manage timelines and budgets, and communicate development milestones to leadership in a fast-paced, innovative

Qualificações

• Ph.D. or BS/MS with extensive small molecule development experience.
• Knowledge of ICH guidelines and cGMPs.
• Ability to manage multiple projects across development stages.

Responsabilidades

• Lead external scientists for route scalability assessment and optimization to deliver API on multi-kilogram scale.
• Collaborate with CDMO partners to manage process development and API manufacturing.
• Represent Drug Substance Development on core teams and subteams.
• Oversee synthetic route design, control strategies, and regulatory starting materials.

Conhecimentos

Process chemistry development

CDMO management

Multi-kilogram scale manufacturing

Communication skills

Project management

Formação académica

PhD +6 years

BS/MS +10 years

Descrição da oferta de emprego

Vividion Therapeutics, Inc. in San Diego seeks a Principal Scientist, Chemical Development to build robust synthetic routes and deliver non-GMP & GMP material on multi-kilogram scale.

You will lead external scientists, coordinate with CDMO partners, and drive API development from preclinical to proof-of-concept across programs. You will collaborate with QA and regulatory teams, manage timelines and budgets, and communicate development milestones to leadership in a fast-paced, innovative