Senior Scientist, Biology

Dualitas Therapeutics; San Francisco (CA); On-site; USD 156,000 - 185,000; Full time

Benefits offered by this job

Annual performance bonus

Equity grants

Comprehensive benefits package

Job summary

Dualitas Therapeutics in South San Francisco, CA, seeks a Senior Scientist to drive discovery and portfolio entry of novel bispecific antibodies through high-throughput screening in cell-based assays. The role emphasizes assay development and execution, while collaborating with biotherapeutics, automation, and computational biology team members.

The ideal candidate combines deep expertise in cell biology and in vitro assays with scientific rigor and the ability to thrive in a fast-paced,

Qualifications

• Extensive cell culture experience with in vitro assay development.
• Hands-on expertise in cell-based reporters, primary immune cells, flow cytometry, ELISA, and MSD.
• Strong ability to develop, optimize and troubleshoot robust assay protocols.
• Preferable familiarity with assay miniaturization and high-throughput screening.
• Demonstrated independent scientific achievement in immunology (INDs, patents, publications).
• Excellent time management and collaboration across disciplines.

Responsibilities

• Drive discovery and portfolio entry of novel bispecific antibodies.
• Lead assay development and execution in cell-based systems.
• Collaborate with biotherapeutics, automation, and computational biology teams.
• Manage multiple projects with strong communication and organization.

Skills

Cell culture

In vitro assay development

Flow cytometry

ELISA

MSD

Time management

Education

BS/MS in Biological Sciences

Job description

At Dualitas Therapeutics, we are redefining bispecific antibody discovery and development for autoimmune disease. Based in South San Francisco, California, our scientists are pioneering innovative technology to advance the next generation of antibody therapeutics. Our employees are our most important asset, and together we are dedicated to making Dualitas a scientifically superb and highly collegial place to work.

Our work at Dualitas Therapeutics is guided by our Operating Principles:

• Get Things Done Creatively as One Team — Propose solutions, align stakeholders, and move the work forward.
• Advance Differentiated Medicines with Scientific Rigor — Apply disciplined clinical development judgment and data-driven decision-making.
• Operate with Urgency, Discipline and Grit — Drive timelines, mitigate risks, and maintain executional focus.

Position Summary

We are seeking a highly motivated Senior Scientist to join our team and drive the discovery and portfolio entry of novel bispecific antibodies through high-throughput screening in cell-based assays. This individual will play a key role in assay development and execution, while collaborating closely with biotherapeutics, automation, and computational biology team members. The ideal candidate combines deep expertise in cell biology and in vitro assays with scientific rigor and the ability to thrive in a fast-paced, collaborative environment. This is an exciting opportunity for a scientist who is eager to make a tangible impact on the discovery of novel therapies for autoimmune diseases.

Qualifications

We’re looking for a strong scientist with hands‑on technical expertise who is curious, proactive, and collaborative.

Extensive cell culture experience.

Hands‑on expertise with in‑vitro assay development, including but not limited to cell‑based reporters, primary immune cells, flow cytometry, ELISA, and MSD.

Ability to develop, optimize, and troubleshoot robust assay protocols.

The following are valued but not essential:

oFamiliarity with assay miniaturization, automation, and high throughput screening.

Demonstrated track record of independent critical thinking and scientific achievement in immunology as evidenced by contributions to INDs, patents, and/or publications.

Proven ability to manage multiple projects independently, with excellent time management and organizational skills.

Strong oral and written communication skills.

Ability to thrive in a highly collaborative, fast‑paced, team‑oriented environment with colleagues from diverse disciplines.

Education

BS/MS in the Biological Sciences with at least 5+ years research experience in cell biology, immunology, or a related field.

Compensation

The expected annual base pay range for this position is $156,000 –$185,000 and will depend on several factors, including but not limited to, the candidate’s experience, skills and competencies. The pay range reflects multiple levels within the Scientist job family. The final title and compensation will be determined based on the candidate’s qualifications and relevant experience.

• This role is eligible for annual performance bonuses, equity grants, and a comprehensive benefits package that includes medical, dental, vision, retirement plan, paid time off, and other employee programs.