Senior Scientist - Biologics Design & Function

Biopharma Careers; North Carolina; On-site; USD 120,000 - 180,000; Full time

Job summary

Johnson & Johnson in Spring House, PA, is seeking a Senior Scientist, Biologics Design & Function to advance therapeutics by translating immune biology into differentiated strategies. You will combine deep immunology expertise with hands-on lab work to evaluate mechanisms of action and optimize biologics across discovery programs.

The role requires independence, strong problem-solving, and the ability to communicate complex findings to multidisciplinary teams.

Qualifications

• Master's degree in Immunology, Cell Biology, Biochemistry, Bioengineering, or a related scientific field is required; a PhD is highly preferred.
• 4+ years of industry experience with a Master's degree; 2+ years with a PhD.
• Deep understanding of immunology, disease biology, and immune cell signaling.
• Experience advancing biologic therapeutics and discovery programs in complex research environments.
• Expertise in designing, developing, and interpreting mechanistic cellular assays using primary human immune cells.

Responsibilities

• Designing, implementing, and interpreting mechanistic and functional studies that guide molecule design and inform program decisions.
• Serving as subject matter expert to apply immunological insights to guide molecule optimization.
• Developing and implementing innovative assays and technologies to understand therapeutic mechanisms.
• Evaluating emerging technologies to accelerate biologics functional assay workflows.
• Demonstrating ability to translate mechanistic insights into actionable therapeutic strategies.
• Communicating scientific findings through presentations, reports, patents, publications, and team discussions.
• Contributing to a culture of scientific excellence, innovation, collaboration, and continuous learning.

Skills

Immunology

Biologics discovery

Cell-based assays

Team leadership

Scientific communication

Education

Master's in Immunology or related

PhD preferred

Tools

Flow cytometry

High-throughput assays

MSD

xCELLigence

Incucyte

Job description

Johnson & Johnson in Spring House, PA, is seeking a Senior Scientist, Biologics Design & Function to advance therapeutics by translating immune biology into differentiated strategies. You will combine deep immunology expertise with hands-on lab work to evaluate mechanisms of action and optimize biologics across discovery programs.

The role requires independence, strong problem-solving, and the ability to communicate complex findings to multidisciplinary teams.