Senior Scientist - Bioanalysis

Millipore Corporation; Billerica (MA); On-site; USD 95,000 - 144,000; Full time

Job summary

EMD Serono in Billerica, MA is seeking a Senior Scientist to join the New Biological Entities Drug Metabolism and Pharmacokinetics (NBE DMPK) team. You will work in a matrixed R&D environment to deliver bioanalytical services for NBEs, ADCs, AOCs, and other biologics from discovery through clinical development.

You will design and validate assays, interpret data, and ensure timely, high-quality deliverables while collaborating with CROs and internal scientists.

Qualifications

• PhD in Biochemistry, Biology, Chemistry, or related science field with 2+ years post-PhD PK/bioanalytics experience.
• 2+ years working with NBEs, ADCs, AOCs, or other novel modalities.

Responsibilities

• Develop and validate bioanalytical methods for sample analysis in discovery and development.
• Support characterization of NBEs, ADCs, AOCs, and other biologics across discovery to clinical stages.
• Ensure timely, high-quality ligand-binding bioanalytical deliverables (method development, qualification, application to in-vivo studies).
• Supervise critical reagent characterization when needed and provide data-driven solutions to project issues.

Skills

Experimental design

Troubleshooting

Data analysis

Data mining

Immunogenicity

Bioanalytical methods

Analytical reporting

Education

PhD in Biochemistry/Biology/Chemistry

Tools

Watson LIMS

GraphPad Prism

Veeva Vault

Job description

Work Your Magic with us! Start your next chapter and join EMD Serono. Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us.

United As One for Patients, our purpose in Healthcare is to help create, improve and prolong lives. We develop medicines, intelligent devices and innovative technologies in therapeutic areas such as Oncology, Neurology and Fertility. Our teams work together across 6 continents with passion and relentless curiosity in order to help patients at every stage of life. Joining our Healthcare team is becoming part of a diverse, inclusive and flexible working culture, presenting great opportunities for personal development and career advancement across the globe.

This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role

EMD Serono in Billerica, MA is hiring a Senior Scientist. The New Biological Entities Drug Metabolism and Pharmacokinetics (NBE DMPK) Senior Scientist role is a scientific and operational role in Research and Development (R&D). Our company is committed to bringing transformational medicines to patients, and you will collaborate in a matrixed environment with other passionate functional experts to deliver novel biotherapeutics.

Responsibilities

Development and fit-for-purpose validation of bioanalytical methods to be applied in sample analysis for molecules in discovery and development phases. Your work will support the characterization of multiple molecules and modalities, including multi-specific NBEs, antibody-drug conjugates (ADCs), antibody oligonucleotide conjugates (AOCs), and other biologics, from molecule design through preclinical and clinical phases, thus fulfilling internal and regulatory requirements. Representative technologies could include innovative immunochemical and ligand binding techniques such as ELISA, MSD-ECLA, Gyrolab, and others. Development of complex experimental study designs, interpretation of analytical data, good knowledge of immunogenicity, and technical report writing according to current company and industry standards. Ensuring timely delivery, with appropriate quality, of ligand-binding assay (LBA) bioanalytical deliverables (method development, qualification, and its application to in-vivo animal studies), and if needed, responsible for conducting/supervising critical reagent characterization. Recommending data decisions to the lab manager by providing solid results, findings and technical solutions to project issues/problems. Conducting scientific literature research to address complex technical issues and evaluate and implement potential new analytical strategies and technologies as needed. Monitoring bioanalytical studies at contract research organizations (CROs).

Minimum Qualifications

• PhD in Biochemistry, Biology, Chemistry, or other Science field, with 2+ years post PhD experience in PK, bioanalytics, immunogenicity, and/or other drug discovery/development experience
• 2+ years of experience with biological molecules (NBEs, ADCs, AOCs, or other novel modalities)

Preferred Qualifications

• Excellent experimental design and troubleshooting skills, and excellent data analysis & data mining skills
• Experience and comfort using, optimizing, and troubleshooting the performance of laboratory instruments
• Ability to prepare bioanalytical method documentation
• Good knowledge of specific software: Watson LIMS, GraphPad Prism, Veeva Vault, etc.
• Knowledge of disease areas (e.g. Immunology, Oncology, etc.), and an understanding of biology and pharmacology
• Excellent organizational skills and both verbal and written communication skills
• Excellent inter-cultural understanding

Pay Range for this position: $94,600 - $144,100. The offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses.

Benefits offered by the Company include health insurance, paid time off (PTO), retirement contributions, and other perquisites.

For more information click here.

What we offer

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!