Senior Scientist, Analytical Development - Large Molecule

Scorpion Therapeutics; Bridgewater (MA); On-site; USD 120,000 - 180,000; Full time

Job summary

Scorpion Therapeutics seeks a Senior Scientist in Large Molecule Analytical Development focused on biologics candidates. You will oversee internal labs and CRO/CMDO activities, drive method development, transfer, and characterization of drug substances and products, and support IND/CTA regulatory documentation.

The role requires PhD with 2+ years in biopharma or a Master's with 4+ years, plus extensive experience in bioanalytical chemistry, chromatography, MS, and biophysical techniques.

Qualifications

• PhD with 2+ years in biopharma or MS with 4+ years, or BS with 6+ years in biopharma.
• Expertise in bioanalytical chemistry, chromatography, MS and biophysical techniques.
• Experience with biologics development, GxP and regulatory guidelines.

Responsibilities

• Lead and manage internal labs and CRO/CMDO analytical activities.
• Develop, qualify, transfer and characterize drug substances and products.
• Support release and stability testing and regulatory submissions.

Skills

Bioanalytical chemistry

Chromatography

Mass spectrometry

Biophysical techniques

Biologics development

Bioinformatics

Sequencing analysis

Software development

Education

PhD in Biopharma/related field

MS in a related field

BS in a related field

Tools

Sequencing analysis software

Biotech data analysis tools

Job description

Role: Senior Scientist in Large Molecule Analytical Development, focusing on biologics drug candidates.

Responsibilities include managing internal labs and overseeing CRO/CMDO analytical activities such as method development, qualification, transfer, and characterization of drug substances and products. The role supports release and stability testing, collaborates with multidisciplinary teams, and authorizes analytical documentation for regulatory submissions like INDs and CTAs.

Requirements:

PhD with 2+ years or Master’s with 4+ years or Bachelor’s with 6+ years in biopharma, with expertise in bioanalytical chemistry, chromatography, mass spectrometry, and biophysical techniques. Experience in biologics development, GxP, and regulatory guidelines is essential. Nice-to-have skills include bioinformatics, software development, and sequencing analysis.

Location: On-site in Bridgewater, NJ, with occasional domestic/international travel (~5-15%).

High-value aspects: biologics, large molecules, preclinical and clinical stages, analytical method development, regulatory documentation, cross-functional collaboration, and GxP environment.