Senior Scientist

Millipore Corporation; Carlsbad (CA); On-site; USD 78,000 - 117,000; Full time

Benefits offered by this job

Health insurance

Paid time off

Retirement contributions

Other perquisites

Job summary

MilliporeSigma in Carlsbad, CA is seeking a skilled Analytical Scientist to support GMP viral vector programs, focusing on validation and transfer of analytical methods.

You will perform complex assays (qPCR, HPLC, ELISA), develop/qualify methods, document SOPs, trend data, and collaborate with QA, Manufacturing and clients to ensure accurate results and regulatory compliance.

Qualifications

• Bachelor's degree in Chemistry, Biochemistry or other life science discipline required.
• 8+ years of experience in GMP environment or QC Laboratory required.
• Master's degree in Chemistry, Biochemistry or related field preferred.
• Experience with analytical techniques ELISA, HPLC/UPLC, qPCR/ddPCR, spectroscopy, cell-based assays and method validation/transfer.

Responsibilities

• Perform complex analytical assays (qPCR, ddPCR, HPLC, CE-SDS, ELISA) on cGMP materials with accuracy and deadlines.
• Lead method development, qualification, validation and tech transfers across sites.
• Author, review, and approve SOPs, protocols, and reports compliant with cGMP/ICH.

Skills

ELISA

HPLC/UPLC

qPCR/ddPCR

Spectroscopy

Cell-based assays

Method validation/transfer

Data trending

Statistics

Instrument maintenance

Basic programming

Education

Bachelor's degree in Chemistry/Biochemistry/Life Sciences

Master's degree preferred

Job description

Work Your Magic with us! Start your next chapter and join MilliporeSigma.Ready to explore, break barriers, and discover more? We know you've got big plans - so do we! Our colleagues across the globe love innovating with science and technology to enrich people's lives with our solutions in Healthcare, Life Science, and Electronics. Together, we dream big and are passionate about caring for our rich mix of people, customers, patients, and planet. That's why we are always looking for curious minds that see themselves imagining the unimaginable with us. This role does not offer sponsorship for work authorization. External applicants must be eligible to work in the US.

Your Role:

MilliporeSigma is seeking a skilled and motivated Analytical Scientist with expertise in validation of analytical methods to support a Viral Vector CDMO Facility in Carlsbad, CA . The successful candidate will be responsible for conducting advanced analytical analyses, transferring and validating analytical methods to support all Phases of GMP Viral Vector client programs and ensuring the accuracy and reliability of test results. The Senior Scientist position, will have a willingness to contribute to the overall success of the company by assisting in many areas beyond specific job duties.

In this role, responsibilities include, but are not limited to:

• Perform complex analytical assays (qPCR, ddPCR, HPLC, CE-SDS, ELISA) on cGMP materials while ensuring strict data accuracy and meeting project deadlines.
• Lead, execute, and manage method development, optimization, qualifications, validations, and tech transfers across internal and external sites.
• Author, review, and approve technical documentation (SOPs, protocols, reports) in full alignment with cGMP, ICH guidelines, and regulatory standards.
• Trend analytical data, document OOS/OOT results, and apply critical thinking to execute root-cause investigations and corrective actions.
• Maintain, troubleshoot, and qualify laboratory instrumentation, partnering with Facilities & Engineering to manage calibration and preventive maintenance.
• Serve as the technical Subject Matter Expert (SME) for QC analytical methods during client interactions, regulatory inspections, and audits.
• Train, coach, and mentor junior scientists while actively promoting a culture of safety, continuous learning, and quality.
• Collaborate across teams (QA, Manufacturing, AD/PD, clients) to design studies, deliver actionable insights, and drive lab efficiency initiatives.

Physical Attributes:

Work in analytical testing lab. Bend, stoop, squat, crawl, kneel, climb, or reach overhead. Wear required PPE such as safety glasses, gloves, masks, and close-toed shoes.

Minimum Qualifications:

• Bachelor's degree in Chemistry, Biochemistry or other life science discipline.
• 8+ years of experience in GMP environment or QC Laboratory.

Preferred Qualifications:

• Master's Degree in Chemistry, Biochemistry or other life science discipline.
• Experience with analytical techniques ELISA, HPLC/UPLC, qPCR/ddPCR, spectroscopy, cell-based assays); method validation/transfer; data trending and statistics; instrument maintenance; basic programming or data analysis tools.
• Experience with cGMP, ICH guidelines, and QA/QC systems; experience with regulatory submissions and deviations/CAPA.
• Experience with Biologics and Virology.
• Experience with QA release testing and GMP documentation.

Pay Range for this position:

$77,900/yr - $116,900/yrThe offer range represents the anticipated low and high end of the base pay compensation for this position. The actual compensation offered will be determined by factors such as location, level of experience, education, skills, and other job-related factors. Position may be eligible for sales or performance-based bonuses.

Benefits offered by the Company include

• health insurance
• paid time off (PTO)
• retirement contributions
• other perquisites

What we offer:

We are curious minds that come from a broad range of backgrounds, perspectives, and life experiences. We believe that this variety drives excellence and innovation, strengthening our ability to lead in science and technology. We are committed to creating access and opportunities for all to develop and grow at your own pace. Join us in building a culture of inclusion and belonging that impacts millions and empowers everyone to work their magic and champion human progress!

For more information.