Senior Research Technologist - Przybyl Lab

ccf; Cleveland (OH); Vor Ort; USD 70.000 - 110.000; Vollzeit

Zusammenfassung

Cleveland Clinic Health System’s Przybyl Lab seeks a Senior Research Technologist to support translational cancer research and develop protocols for NGS library preparation. You will help interpret results, troubleshoot experiments, and contribute to advancing sarcoma biomarker discovery.

The role involves lab supervision, protocol development, and collaboration with a multidisciplinary team in a leading healthcare research environment on the Cleveland Clinic Main Campus.

Qualifikationen

• Experience with translational cancer research protocols.
• Ability to design/interpret experiments and maintain project documents.
• Experience with multi-omic approaches across genomic, transcriptomic, proteomic, methylome.

Aufgaben

• Supervise a research lab and manage day-to-day operations.
• Assist with experimental design and technical planning.
• Organize protocols, maintain records and documentation.
• Present findings and assist with publications.

Kenntnisse

Lab techniques

Cancer cell culture

Genetic manipulation

Library construction (NGS)

Bioinformatics basics

Ausbildung

Bachelor's degree in a related field

Master's degree in related field

Associate's degree in related field

High School Diploma with experience

Tools

Next-gen sequencing

PCR/ RT-qPCR

Cell culture facilities

Jobbeschreibung

At Cleveland Clinic Health System, we believe in a better future for healthcare. And each of us is responsible for honoring our commitment to excellence, pushing the boundaries and transforming the patient experience, every day.

We all have the power to help, heal and change lives — beginning with our own. That’s the power of the Cleveland Clinic Health System team, and The Power of Every One.

Job Title

Senior Research Technologist - Przybyl Lab

Location

Cleveland

Facility

Cleveland Clinic Main Campus

Department

RES Center for Computational Life Sciences-Research Innov and Educ

Job Code

D99762

Shift

Days

Schedule

8:00am-5:00pm

Job Summary

Job Details

Join Cleveland Clinic’s Main Campus where research and surgery are advanced, technology is leading-edge, patient care is world class and caregivers are family. Here, you will work alongside a passionate and dedicated team, receive endless support and appreciation, and build a rewarding career with one of the most respected healthcare organizations in the world.

The Laboratory of Dr. Joanna Przybyl is seeking a Research Technologist to participate in translational cancer research. The Przybyl lab develops novel clinically applicable liquid biopsy testing methods for sarcoma and applies multi-omic (genomic, transcriptomic, proteomic and methylome) high-throughput methods to discover new biomarkers and new therapies for sarcoma.

Read more about the Przybyl Lab: https://www.lerner.ccf.org/computational-medicine/przyby/

The selected candidate will apply well-established protocols and develop novel protocols for library preparation for next-generation sequencing and perform functional studies to investigate therapeutic targeting of metabolic pathways in sarcoma models. The selected candidate will assist in the interpretation of the results and troubleshooting technical issues.

A caregiver in this position works Monday through Friday from 8:00 a.m. - 5:00 p.m.

A caregiver who excels in this role will:

• Supervise a research lab on a daily basis, including space, equipment, personnel, and project management.
• Assist staff investigator with experimental design and planning/developing technical aspects of research projects.
• Plan, organize, perform, and monitor daily project protocols.
• Collect, prepare, and maintain required research documentation, including informed consent records, case records, clinical notes, and medical reports.
• Report and assist with the management of protocol deviations, adverse events, and other project-related issues.
• Assist with the preparation and delivery of internal/external presentations, conference reports/lectures, and publishing submissions.
• Maintain specimen database for the laboratory projects.
• Perform ongoing literature review to remain current with new procedures and related research.
• Propose new research directions based on new advances discussed in literature.
• Perform general maintenance duties of a "wet" lab facility, such as maintenance of stock solutions, inventory, cell lines, and all necessary functions associated with the performed studies.
• Other duties as assigned.

Minimum qualifications for the ideal future caregiver include:

• High School Diploma and six years of experience in a research or related laboratory environment, which has developed the ability to work independently on a variety of research projects, demonstrated through a thorough understanding of research laboratory techniques and procedures
• OR Associate's in laboratory science field and five years of experience in a research or related laboratory environment
• OR Bachelor's degree and four years of experience in a research or related laboratory environment
• OR Master's degree and three years of experience in a research or related laboratory environment
• Proficientin innovative design and development techniques, with experience in budget management

Preferred qualifications for the ideal future caregiver include:

• Expertise in cancer cell culture techniques and genetic manipulation, library construction for next generation sequencing, molecular biology techniques, and molecular studies of patient-derived specimens
• Experience in supervising or mentoring junior lab members
• Experience in bioinformatics and/or quantitative data analysis
• Experience in library construction for next generation sequencing
• Experience with Tissue Culture

Physical Requirements

• Ability to perform work in a stationary position for extended periods
• Ability to operate a computer and other office equipment
• Ability to communicate and exchange accurate information
• Ability to distinguish color
• Manual dexterity to handle specimens and repair equipment
• Ability to lift and transport equipment or specimens up to 20 pounds
• May be exposed to hazardous chemicals, bio-hazards, radioactive materials, etc.

Personal Protective Equipment

• Follows standard precautions using personal protective equipment as required.

The policy of Cleveland Clinic Health System and its system hospitals (Cleveland Clinic Health System) is to provide equal opportunity to all of our caregivers and applicants for employment in our drug free environment. All offers of employment are followed by testing for controlled substances.

Cleveland Clinic Health System administers an influenza prevention program. You will be required to comply with this program, which will include obtaining an influenza vaccination on an annual basis or obtaining an approved exemption.

Decisions concerning employment, transfers and promotions are made upon the basis of the best qualified candidate without regard to color, race, religion, national origin, age, sex, sexual orientation, marital status, ancestry, status as a disabled or Vietnam era veteran or any other characteristic protected by law. Information provided on this application may be shared with any Cleveland Clinic Health System facility.

If applying for a Florida position, please see the following website for more information on the background screening requirements required by the Agency of Health Care Administration: https://info.flclearinghouse.com/

Please review the Equal Employment Opportunity poster.

Cleveland Clinic is pleased to be an equal employment opportunity employer.