Senior Research Technician — Antibiotic Discovery Platform

Northeastern University; Boston (MA); On-site; USD 40,000 - 56,000; Full time

Job summary

The Antibiotic Discovery Center (ADC) at Northeastern University is seeking a highly motivated Senior Research Technician to support the development and implementation of a target-based screening platform for antibiotic discovery, assist in downstream hit validation and compound isolation, and contribute to overall laboratory operations in a collaborative research environment.

The role involves developing a microfluidics-based high-throughput screening platform, executing assays, and supporting

Qualifications

• Bachelor’s or Master’s degree in Microbiology, Biochemistry, Chemistry, Molecular Biology, or a related field.
• Minimum 2–3 years of hands-on research experience in an academic or industrial setting.
• Technical expertise in molecular cloning, bacterial culture, and biochemical or enzymatic assays.

Responsibilities

• Develop a microfluidics-based high-throughput screening platform.
• Execute biochemical and microbiological assays to identify and validate antibacterial targets.
• Support high-throughput and focused screening efforts, including assay development, optimization, and data analysis.
• Participate in hit triage, secondary assays, and compound characterization, including natural product isolation and structure–activity studies.
• Operate and maintain equipment supporting screening and compound purification (e.g., LC, HPLC, plate readers, microfluidics sorters).
• Manage lab inventories, supplies, and safety compliance; coordinate maintenance and calibration of shared instruments.
• Contribute to protocol development, data management, and preparation of reports and presentations.
• Provide training and technical support to students and new lab members.

Skills

Molecular cloning

Bacterial culture

Biochemical assays

Analytical instrumentation

Education

Bachelor’s or Master’s degree in Microbiology/biochemistry/molecular biology

Tools

LC-MS

Job description

The Antibiotic Discovery Center (ADC) at Northeastern University is seeking a highly motivated Senior Research Technician to support the development and implementation of a target-based screening platform for antibiotic discovery, assist in downstream hit validation and compound isolation, and contribute to overall laboratory operations in a collaborative research environment.

The role involves developing a microfluidics-based high-throughput screening platform, executing assays, and supporting