Senior Research Scientist, Translational Neuroscience, AI & Biomarker Discovery

Thornton Tomasetti; Plano (TX); On-site; USD 78,000 - 156,000; Full time

Benefits offered by this job

Free HIP PPO medical coverage

Excellent retirement plan

Tuition reimbursement

Education benefits (FreeU)

Global company recognition

Job summary

Abbott Neuromodulation seeks a Senior Research Scientist to advance translational neuroscience and biomarker discovery. You will design preclinical and clinical studies, integrate multimodal data, and apply AI/ML to uncover therapeutic mechanisms and predictors of response.

The role requires PhD-level expertise, 5+ years in neuroscience or neuromodulation, and strong collaboration across research, clinical, engineering, and regulatory teams.

Qualifications

• PhD in Neuroscience or related discipline with postdoctoral or industry experience.
• 5+ years of experience in neuroscience or neuromodulation research.
• Experience designing preclinical and/or clinical studies.
• Knowledge of biomarkers and multimodal data analysis.
• Strong communication and collaboration skills.

Responsibilities

• Design and execute preclinical, translational, and clinical studies on neuromodulation.
• Test hypotheses on treatment response, neuroplasticity, and outcomes.
• Integrate molecular, genetic, electrophysiological, imaging, behavioral, and digital data.
• Identify and validate biomarkers for therapeutic response and MoA.
• Apply AI/ML to derive insights from complex datasets.
• Collaborate with bioinformatics, engineering, clinical, and regulatory teams.
• Analyze omics datasets to explore mechanisms and outcomes.
• Publish findings and present to stakeholders.
• Support external collaborations with academia and industry.

Skills

Neuroscience

Biomarker biology

AI/ML in bioscience

Scientific communication

Cross-functional collaboration

Education

PhD in Neuroscience or related field

Tools

EEG

Neuroimaging

Omics data analysis

Wearable sensors

Computational biology tools

Job description

Abbott is a global healthcare leader that helps people live more fully at all stages of life. Our portfolio of life-changing technologies spans the spectrum of healthcare, with leading businesses and products in diagnostics, medical devices, nutritionals and branded generic medicines. Our 122,000 colleagues serve people in more than 160 countries.

Senior Research Scientist Translational Neuroscience, AI & Biomarker Discovery

Working at Abbott, you can do work that matters, grow, and learn, care for yourself and your family, be your true self, and live a full life.

Benefits

• Career development with an international company where you can grow the career you dream of.
• Employees can qualify for free medical coverage in our Health Investment Plan (HIP) PPO medical plan in the next calendar year.
• An excellent retirement savings plan with a high employer contribution.
• Tuition reimbursement, the Freedom 2 Save student debt program, and FreeU education benefit - an affordable and convenient path to getting a bachelor's degree.
• A company recognized as a great place to work in dozens of countries worldwide and named one of the most admired companies in the world by Fortune.
• A company that is recognized as one of the best big companies to work for as well as the best place to work for diversity, working mothers, female executives, and scientists.

The Opportunity Abbott Neuromodulation is seeking a Senior Research Scientist to contribute to innovative translational research programs focused on understanding the mechanisms of neuromodulation and advancing next-generation therapies. In this role, you will design and execute preclinical and clinical studies that integrate neuroscience, molecular biology, genetics, electrophysiology, digital health, and artificial intelligence to uncover biological drivers of therapeutic response. You will collaborate across research, clinical, engineering, regulatory, and data science teams to generate scientific evidence that informs therapy development, biomarker discovery, and personalized treatment approaches. This position is ideal for a scientifically curious and hands-on researcher who enjoys combining experimental design, data analysis, and translational science to solve complex biological and clinical questions.

What You'll Do

• Design and execute preclinical, translational, and clinical research studies investigating the biological and physiological mechanisms of neuromodulation.
• Develop and test hypotheses related to treatment response, neuroplasticity, neural signaling, and therapeutic outcomes.
• Conduct multimodal studies integrating molecular, genetic, electrophysiological, imaging, behavioral, digital, and clinical datasets.
• Contribute to the identification and validation of biomarkers associated with treatment response and mechanism of action.
• Apply AI, machine learning, and advanced analytical methods to generate insights from complex biological and clinical data.
• Collaborate with bioinformatics, data science, engineering, clinical, and regulatory teams to advance research programs.
• Evaluate genomic, transcriptomic, proteomic, metabolomic, epigenetic, and other omics datasets to investigate biological mechanisms and therapeutic outcomes.
• Analyze and interpret research findings and communicate results to scientific and cross-functional stakeholders.
• Author scientific publications, technical reports, conference presentations, and invention disclosures.
• Support collaborations with academic investigators, clinical researchers, and external research partners.

Required Qualifications

• PhD in Neuroscience, Neurobiology, Molecular Biology, Genetics, Biomedical Engineering, Systems Biology, Computational Biology, Bioinformatics, or a related scientific discipline.
• 5+ years of postdoctoral, industry, or equivalent research experience in neuroscience, neurotechnology, biotechnology, pharmaceuticals, medical devices, or related fields.
• Experience designing and executing preclinical and/or clinical research studies.
• Knowledge of one or more of the following areas: Neuroscience or Neurophysiology; Neuromodulation; Biomarker Discovery; Molecular Biology or Genetics; Systems Biology or Computational Biology; Bioinformatics; Artificial Intelligence or Machine Learning applied to biological or clinical datasets.
• Experience analyzing and interpreting biological, physiological, and clinical datasets.
• Strong scientific communication and collaboration skills.
• Demonstrated record of scientific publications and research accomplishments.

Preferred Qualifications

• Experience in chronic pain, movement disorders, psychiatric disorders, or other neuromodulation-related therapeutic areas.
• Experience with EEG, ECAPs, neuroimaging, wearable sensors, digital biomarkers, or electrophysiological signal analysis.
• Experience working with genomic, transcriptomic, proteomic, metabolomic, or other omics datasets.
• Experience integrating multimodal datasets to investigate mechanisms of disease or therapeutic response.
• Familiarity with machine learning, predictive modeling, or AI applications in healthcare and life sciences.
• Experience working in cross-functional environments spanning research, engineering, clinical, and regulatory organizations.

Compensation

The base pay for this position is $78,000.00 - $156,000.00. In specific locations, the pay range may vary from the range posted.

Location

Research and Discovery Family: Research and Discovery Divison: NM Neuromodulation. Location: United States > Texas > Plano: 6901 Preston Road. Additional Locations: Not specified. Work Shift: Standard. Travel: Not specified. Medical Surveillance: Not Applicable.

Significant Work Activities

• Continuous sitting for prolonged periods (more than 2 consecutive hours in an 8 hour day).
• Continuous standing for prolonged periods (more than 2 consecutive hours in an 8 hour day).
• Continuous walking for prolonged periods (more than 2 hours at a time in an 8 hour day).

EEO Statement

Abbott is an Equal Opportunity Employer of Minorities/Women/Individuals with Disabilities/Protected Veterans. EEO is the Law link - English: http://webstorage.abbott.com/common/External/EEO_English.pdf EEO is the Law link - Espanol: http://webstorage.abbott.com/common/External/EEO_Spanish.pdf Abbott is an Equal Opportunity Employer, committed to employee diversity.

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