Research Associate, Cellular Immunology ( 6 Month Contract)

Monte Rosa Therapeutics; Boston (MA); On-site; USD 70,000 - 100,000; Full time

Job summary

Monte Rosa Therapeutics is seeking an energetic and highly motivated Contractor located in Boston to support the development and characterization of novel molecular glue degraders for inflammatory diseases. This role supports Immunology projects from early lead optimization through clinical-stage.

The ideal candidate should have an MS or PhD in Immunology or Cell Biology with over 3 years of relevant experience, and demonstrate a strong collaborative spirit to meet team goals.

Qualifications

• 3+ years of hands-on experience in I&I drug discovery research in a pharmaceutical setting.
• Extensive experience handling whole blood, primary immune cells, and tissue samples.
• Expertise in protein detection/quantitation methodology.

Responsibilities

• Design, optimize, and execute experiments using various primary immune cells and tissues.
• Routine profiling of compounds using MSD, ELISA, Western blot, and flow cytometry.
• Maintain detailed notes using electronic lab notebook.

Skills

Immunology knowledge

Cell Biology expertise

Flow cytometry

Experimental design

Protein detection methods

Microsoft Excel proficiency

GraphPad Prism

Education

MS or PhD in Immunology or Cell Biology

Tools

Meso Scale Discovery (MSD)

ELISA

Western blot

Job description

Monte Rosa Therapeutics is seeking an energetic and highly motivated Contractor located in Boston to support the development and characterization of novel molecular glue degraders for the treatment of inflammatory diseases. As part of the Immunology and Preclinical Pharmacology team, this role will broadly support multiple immunology and inflammation (I&I) projects/programs from early lead optimization through clinical-stage.

The ideal candidate is an experienced experimentalist with a strong background in I&I and a demonstrated ability to work collaboratively to achieve team/company goals.

• Design, optimize and execute experiments using a variety of primary immune cells and tissues isolated from human, mouse or cynomolgus monkey (including PBMCs, monocyte‑derived macrophages, whole blood, synovial fluid, peritoneal fluid, etc.)
• Routine profiling of compounds using Meso Scale Discovery (MSD), ELISA, Western blot, Simple Western (Jess), flow cytometry, qPCR assays
• Ex vivo mouse tissue processing (spleen, bone marrow, lymph node, etc.)
• Maintain timely and detailed notes using electronic lab notebook
• MS or PhD equivalent in Immunology or Cell Biology with 3+ years of hands‑on experience in I&I drug discovery research in a pharmaceutical setting
• Extensive experience handling whole blood, primary immune cells and tissue (preferably including clinical samples)
• Expert in protein detection/quantitation methodology (e.g., MSD, ELISA, Western blotting, Jess)
• Flow cytometry expertise is preferred
• Highly proficient with Microsoft Excel, GraphPad Prism (FlowJo is preferred)