Senior Research Associate, Bioanalytical

Sci.bio Recruiting; Boston (MA); On-site; USD 65,000 - 95,000; Full time

Job summary

Sci.bio Recruiting seeks a Research Associate or Senior Research Associate, Bioanalytical Sciences, to support discovery, pharmacology, and preclinical programs with MSD-based immunoassays. This bench-focused role emphasizes assay development, troubleshooting, and data interpretation within cross-functional teams.

The candidate will prepare samples, optimize methods, and ensure accurate records while collaborating with CRO partners as needed.

Qualifications

• BS + 3 years or MS + 1 year of hands-on lab experience in biotech/pharma/CRO.
• Degree in biochemistry, molecular biology, immunology, bioengineering or related.
• Hands-on MSD ELISA assays required.
• Knowledge of ligand-binding assays and standard curve analysis.
• Experience with cell culture and basic statistics.
• Proficiency with GraphPad Prism and Excel; ELN/LIMS knowledge (Benchling).
• Strong communication and ability to work independently and manage studies.

Responsibilities

• Execute MSD ELISA immunoassays for PK, biodistribution, and biomarker studies.
• Develop, optimize, and qualify MSD methods including validation of accuracy and precision.
• Prepare tissue and cell samples for quantitative analysis.
• Analyze, interpret, and present bioanalytical data to cross-functional teams.
• Maintain accurate laboratory records and ensure GMP-like compliance where applicable.
• Support assay transfers to CRO partners and manage reagent inventory.

Skills

MSD ELISA

GraphPad Prism

Excel

Cell culture

Data analysis

Independent work

Communication skills

ELN/LIMS (Benchling)

Education

BS + 3 years

MS + 1 year

Biochemistry/Molecular biology/Immunology/Bioengineering

Tools

Benchling

Job description

Contract Research Associate / Senior Research Associate, Bioanalytical Sciences

Position Overview

We are seeking a Research Associate or Senior Research Associate, Bioanalytical Sciences to support discovery, pharmacology, and preclinical development programs. This is a hands-on, bench-focused role centered on the execution, troubleshooting, optimization, and development of quantitative bioanalytical assays, with a strong emphasis on MSD-based immunoassays.

Key Responsibilities

• Execute MSD ELISA immunoassays supporting pharmacokinetic, biodistribution, target engagement, and biomarker studies.
• Develop, optimize, and qualify MSD methods, including reagent selection, titration, matrix/interference assessment, spike recovery, parallelism, dilutional linearity, precision, assay range, and analyte stability.
• Prepare biological samples for quantitative analysis, including tissue homogenization and cell lysate preparation.
• Analyze, interpret, and present bioanalytical data to cross-functional discovery teams.
• Maintain accurate laboratory records and ensure adherence to protocols and applicable requirements.
• Support laboratory operations, reagent inventory, and assay transfers to external CRO partners as needed.

Qualifications

• BS + 3 years or MS + 1 year of hands-on laboratory experience in biotech, pharma, CRO, or a related setting.
• Degree in biochemistry, molecular biology, immunology, bioengineering, or a related discipline.
• Hands-on experience with MSD ELISA assays is required.
• Working knowledge of ligand-binding assays, including assay design, reagent selection, matrix effects, and standard curve analysis.
• Experience with cell culture, transfection, iPSCs, or primary cell culture is a plus.
• Proficiency with GraphPad Prism and Excel and comfort applying basic statistics to quantitative assay data.
• Experience with an ELN/LIMS such as Benchling and strong documentation practices.
• Strong communication skills with the ability to work independently, manage multiple studies, and meet timelines with minimal supervision.

What We Offer

An opportunity to work in a highly collaborative biotech environment supporting innovative therapeutic programs, with competitive compensation, benefits, and opportunities for professional growth.