Senior/Research Associate

NewLimit; South San Francisco (CA); On-site; USD 75,000 - 100,000; Full time

Benefits offered by this job

Health, dental, and vision insurance

401(k) with company match

Paid parental leave

20 days/year paid time off

Meals and snacks on-site

Job summary

A biotechnology company is seeking a Senior/Research Associate to support the development of in vitro assays and pre-clinical models for age-related diseases in South San Francisco. The ideal candidate will have a Bachelor’s degree in a related field and 2-5 years of experience. Responsibilities include isolating cells, developing models, and collaborating across teams. Generous benefits include health insurance, 401(k), paid parental leave, and 20 days PTO.

Qualifications

• 2-5 years of relevant industry or academic experience.
• Proficiency in primary mammalian cell culture and animal handling techniques.
• Exceptional organizational skills, as demonstrated by detailed record-keeping.

Responsibilities

• Isolate cells from primary tissues to optimize in vitro functional assays.
• Develop pre-clinical models of age-related dysfunction.
• Analyze and interpret experimental data to drive preclinical decision making.

Skills

Primary mammalian cell culture

Flow cytometry techniques

Animal handling techniques

Organizational skills

Education

Bachelor’s degree in cell biology, molecular biology, biochemistry or a related field

Tools

Computational tools (e.g. Python, R)

Job description

NewLimit is a biotechnology company working to radically extend human healthspan. We’re developing medicines to treat age-related diseases by reprogramming the epigenome, a new therapeutic mechanism to restore regenerative potential in aged and diseased cells. We leverage functional genomics, pooled perturbation screening, and machine learning models to unravel the biology of epigenetic aging and disease using experiments of unprecedented scale.

Position

NewLimit is seeking an Senior/Research Associate with experience in discovery biology to join our Vascular therapeutic team. Our Vascular program is developing reprogramming medicines to restore youthful function in aged endothelial cells for the treatment of renal, cardiometabolic, and cognitive diseases.

Your role will focus on supporting the development of in vitro assays and pre‑clinical models to measure the functional decline that occurs in endothelial cells with age. You will collaborate closely with our scientists as well as our technology‑focused teams to help create the first reprogramming medicines for the vascular tissue.

What you’ll do

• Isolate cells from primary tissues to optimize in vitro functional assays
• Develop pre‑clinical models of age‑related dysfunction
• Collaborate with our Single Cell Technology, Epigenetic Editing, and Predictive Modeling teams to design, build, and test epigenetic reprogramming interventions at scale
• Support the development of invivo nucleic acid delivery methods for endothelial cells
• Analyze and interpret experimental data to drive pre‑clinical decision making

Requirements

• Bachelor’s degree in cell biology, molecular biology, biochemistry or a related field with 2‑5years of relevant industry or academic experience
• Proficiency in primary mammalian cell culture and animal handling techniques for rodent models
• Proficiency in flow cytometry techniques
• Exceptional organizational skills, as demonstrated by detailed record‑keeping in a lab notebook and an ability to effectively carry out multiple ongoing projects or experiments

Nice to have

• Experience with isolation and functional characterization of primary cells
• Experience developing animal models of cell dysfunction and/or injury
• Experience with FACS and flow cytometry
• Experience using computational tools to automate routine data analysis (e.g. Python, R, etc.)

NewLimit offers generous benefits to ensure our team can focus on our mission:

• Health, dental, and vision insurance
• 401(k) with company match
• Paid parental leave
• Industry‑leading paid time off (PTO) — 20 days/year for all employees + holidays
• Meals and snacks on‑site

Salary Range: $75,000 to $100,000. Compensation for the role will depend on a number of factors, including a candidate’s qualifications, skills, competencies, and experience. NewLimit offers a competitive benefits package, which includes a 401k, healthcare coverage, and 20 days of PTO. Learn more at: https://www.newlimit.com/careers *This compensation and benefits information is based on Company's good faith estimate as of the date of publication and may be modified in the future.