Senior Real-World Evidence & HTA Statistician

Cytel; Augusta (ME); On-site; USD 120,000 - 180,000; Full time

Job summary

Cytel Inc. is seeking a Medical Affairs & HTA Statistician to provide strategic and technical statistical expertise across the product lifecycle, with emphasis on real-world evidence and health technology assessment.

The role translates clinical and observational data into robust evidence for patients, clinicians, payers, and healthcare systems, requiring strong statistical methods, scientific judgement, and cross-functional collaboration at scale.

Qualifications

• Senior-level statistical/biostatistical experience in pharma or healthcare.
• Proven experience delivering Medical Affairs and/or HTA statistical work packages.
• Broad methodological expertise across clinical, observational, and real-world data.
• Strong scientific judgement, strategic thinking, and stakeholder-management skills.

Responsibilities

• Provide statistical leadership for Medical Affairs and HTA evidence-generation activities.
• Support development of evidence strategies addressing clinical, patient, payer, and healthcare-system questions.
• Design and analyse observational and real-world evidence studies.
• Apply epidemiological and statistical methodologies to real-world and clinical data.
• Conduct comparative-effectiveness assessments and indirect treatment comparisons.
• Support synthetic-control approaches, Phase IV studies, and other post-approval evidence-generation activities.
• Apply HTA/HEOR methodologies and contribute statistical expertise to evidence packages supporting access and reimbursement decisions.
• Assess data relevance and quality, quantify and communicate uncertainty, and strengthen methodological credibility of HTA submissions and scientific discussions.
• Interpret clinical and observational evidence and translate analyses into clear scientific conclusions.
• Support publications, congress activities, and other scientific communications where required.
• Apply modern analytical methods, including machine learning, where scientifically appropriate.
• Collaborate with Development Statistics, Epidemiology, Real-World Evidence teams, Medical functions, and external scientific partners.
• Communicate statistical concepts and findings effectively to cross-functional and external stakeholders.

Skills

Statistical leadership

Cross-functional collaboration

Strategic thinking

Stakeholder management

Scientific communication

Tools

R (R language)

Machine learning techniques

Job description

Cytel Inc. is seeking a Medical Affairs & HTA Statistician to provide strategic and technical statistical expertise across the product lifecycle, with emphasis on real-world evidence and health technology assessment.

The role translates clinical and observational data into robust evidence for patients, clinicians, payers, and healthcare systems, requiring strong statistical methods, scientific judgement, and cross-functional collaboration at scale.