Senior Quantitative PK/PD Project Leader

BioSpace; Indianapolis (IN); On-site; USD 153,000 - 246,000; Full time

Benefits offered by this job

Company bonus

401(k) plan

Pension

Medical insurance

Dental insurance

Vision insurance

Vacation benefits

Job summary

Lilly in Indianapolis seeks a dynamic Quantitative Clinical Pharmacologist to provide PK/PD leadership and drive model-based decision-making across the portfolio. You will guide dose selection, patient population, and development strategy with cross-functional teams worldwide.

You will collaborate with PBPK, QSP, and Pharmacometrics modelers to deliver quantitative insights, lead PK/PD analyses, and contribute to regulatory submissions and publications.

Qualifications

• PhD in Pharmaceutical Sciences or related discipline required.
• Minimum 2 years drug development/regulatory experience in quantitative PK/PD, PBPK, or Pharmacometrics.

Responsibilities

• Provide PK/PD leadership to project teams for dose selection and strategy.
• Collaborate with PBPK, QSP, and Pharmacometrics modelers.
• Lead and conduct exploratory PK/PD analyses in early development.
• Deliver study protocols, analysis plans, and reports across Phase I–III.

Skills

Pharmacokinetics

Clinical pharmacology

MIDD approaches

Communication

Collaboration

Education

PhD in Pharmaceutical Sciences

Tools

NONMEM

Monolix

R

SimCYP

GastroPlus

PK-Sim

MATLAB

Job description

Lilly in Indianapolis seeks a dynamic Quantitative Clinical Pharmacologist to provide PK/PD leadership and drive model-based decision-making across the portfolio. You will guide dose selection, patient population, and development strategy with cross-functional teams worldwide.

You will collaborate with PBPK, QSP, and Pharmacometrics modelers to deliver quantitative insights, lead PK/PD analyses, and contribute to regulatory submissions and publications.