Principal Scientist - Precision Medicine

Regeneron Pharmaceuticals, Inc (USA); Village of Tarrytown (NY); Sur place; USD 129 000 - 210 000; Plein temps

Avantages offerts par ce poste

Annual bonus

Equity awards

Pension/retirement benefits

401(k) company match

Health and wellness programs

Fitness centers

Insurance benefits

Paid time off

Family support benefits

Résumé du poste

Regeneron Pharmaceuticals, Inc (USA) is seeking a Principal Scientist, Precision Medicine Strategy Lead focused on solid tumor oncology, heme malignancies, and immune oncology. The role centers on designing robust biomarker strategies and coordinating cross-functional teams to advance clinical development.

You will drive assay development, data integration across genomics, transcriptomics, and proteomics, and guide patient stratification to steer therapeutic decisions.

Qualifications

• Ph.D., M.D., or MS required.
• 4–7 years' cross-disciplinary pharmaceutical/biotech experience.
• Strong communication and presentation skills.

Responsabilités

• Lead focused assay development and implementation across trials.
• Coordinate data analysis with computational scientists for multi-omic data (genomics, transcriptomics, proteomics).
• Interpret results and communicate impact to guide clinical development strategy.
• Enable advances in target identification, indication selection, and patient stratification.
• Partner with Research, Clinical Development, Clinical Pharmacology, CDx, Biostatistics, and Clinical Operations for scientific alignment.
• Manage internal and external collaborations for translational research.
• Contribute to technical reports, study memos, clinical study reports, and publications.

Connaissances

Biomarker strategy

Cross-functional collaboration

Data interpretation

Scientific communication

Formation

Ph.D./M.D./MS

Description du poste

Principal Scientist, Precision Medicine (Biomarker) Strategy Lead Precision Medicine

Build our future together: The Precision Medicine department at Regeneron is responsible for designing and executing the overarching translational and clinical biomarker strategies for therapeutic candidates during clinical development.

We are seeking to hire a Precision Medicine Strategy Lead at the Principal Scientist level focusing on solid tumor oncology, heme malignancies, and immune oncology.

In this highly matrixed role, the Principal Scientist will be responsible for defining the key scientific questions relating to the drug target mechanism of action, disease biology and prognostic biomarkers associated with disease heterogeneity and severity, as well as informing potential patient stratification or selection. This information will guide development of a robust Precision Medicine strategy.

When & where: Location: Tarrytown, NY United States

Discover your role: Leading focused assay development and implementation of assays and associated sample collections throughout a clinical trial. Coordinating data analysis through collaboration with computational scientists involved in integrating multi-omic data: genomics, transcriptomics, and proteomics. Interpreting results and leading communication of the key impact of the data to guide decision making to inform the clinical development strategy. Enabling advances in target identification, indication selection, early indication of biological activity and patient stratification/selection. Partnering cross-functionally across Research, Clinical Development, Clinical Pharmacology, Companion Diagnostics, Biostatistics, and Clinical Operations to ensure seamless scientific alignment. Managing internal and external research collaborations to enable development of clinical fit for purpose assays and translational research. Contributing to technical reports, study memos, clinical study reports, and scientific publications.

This role requires: The ability to drive, manage, execute and deliver timely results for complex scientific projects. Strong communication and presentation skills. A strategic understanding of the application of biomarker technologies to basic, translational or clinical research. Demonstrated ability to effectively collaborate and work in cross-functional teams. A Ph.D., M.D., or MS and 4-7 years' experience participating effectively on cross-disciplinary teams in pharmaceutical or biotech.

Does this sound like you?

We are committed to building a workplace with an inclusive culture.

Regeneron is an equal opportunity employer and all qualified applicants will receive consideration for employment without regard to race, color, religion or belief (or lack thereof), sex, sexual orientation, gender identity or expression, gender reassignment, marital or civil partnership status, civil status, pregnancy or parental status, age, disability, nationality, citizenship status, ethnic or national origin, membership of the Traveler community, familial status, genetic information, military or veteran status, or any other characteristic protected under applicable law.

Where required, we will provide reasonable accommodation to applicants with known disabilities or chronic illnesses during the recruitment process, unless such accommodation would impose undue hardship.

Where necessary, we disclose salary ranges for roles in all countries in which we operate. The final offer will be determined within the relevant range based on the country of employment, specific role level, and your skills and experience. In some countries, collective bargaining agreements (CBAs) may apply and influence certain elements of pay or benefits.

Regeneron offers a competitive and comprehensive total rewards package which may include, depending on country and role: annual bonuses or other incentive plans, equity awards, pension or retirement benefits, 401(k) company match, health and wellness programs, fitness centers, insurance benefits (e.g. medical, dental, vision, life and disability), paid time off, and family support benefits.

For additional information about Regeneron benefits in the U.S., please visit https://careers.regeneron.com/en/working-at-regeneron/total-rewards/. For other locations, additional information will be provided during the recruitment process.

Please be advised that at Regeneron, we believe we do our best work when we are together.

For that reason, many roles are required to be performed on‑site.

As part of the recruitment process, certain background checks may be conducted in accordance with the laws of the country where the position is based. The purpose of such checks is to verify certain information prior to the commencement of employment such as identity, right to work and educational qualifications.

For jobs in Canada: this posting is for an existing position.

Salary Range (annually) $128,600.00 - $210,000.00

Regeneron is a leading biotechnology company that invents life-transforming medicines for people with serious diseases. Founded and led for over 30 years by physician-scientists, our unique ability to repeatedly and consistently translate science into medicine has led to nine FDA-approved treatments and numerous product candidates in development, almost all of which were homegrown in our laboratories. Our medicines and pipeline are designed to help patients with eye diseases, allergic and inflammatory diseases, cancer, cardiovascular and metabolic diseases, neurology, infectious diseases and rare diseases. Regeneron is also proud of award winning culture of innovation, being recognized as a Great Place to Work in 2021, Fast Company’s Best Workplace for Innovators in 2020, and Forbes JUST companies in 2020, among others.