Senior Product Manager, AI-Driven Clinical RWD

Natera; United States; Remote; USD 166,000 - 207,000; Full time

Job summary

Natera’s Real-World Data ClinicalAI team seeks a product manager who will own the end-to-end experience for the platform used by clinicians and data scientists, translating stakeholder needs into reliable automation.

You will shadow users, write requirements, and drive ideas to rollout, partnering with engineering, QA, and clinical teams to improve efficiency and output quality.

If you enjoy turning complex workflows into simple interfaces and measuring adoption with KPIs, this role will suit you.

Qualifications

• Bachelor's degree or equivalent practical experience; 5+ years PM experience.
• Experience owning workflow software used by expert users.
• Hands-on agentic AI experience; shipped LLM-based products.
• AI-native working style; use AI to accelerate product discovery.
• Track record delivering AI workflows end-to-end to stakeholders.
• Keen UX sensibility; complex workflows turned into intuitive interfaces.
• Hands-on user research; shadow users and run usability tests.
• Experience rolling out changes to large distributed user groups.
• Hands-on with data; write SQL or similar to check status.

Responsibilities

• Own the user-experience backlog and priorities for the user-facing application, including case review and editing, document navigation and evidence, work queues, and administrative review, in line with the overall platform roadmap.
• Increase efficiencies without tradeoffs to accuracy: shadow end users, measure where the time goes, and validate problems before they become backlog commitments.
• Turn intricate, multi-step review workflows into clear, intuitive interfaces.
• Own how new AI capabilities appear to end users; define the experience, pilot with leads, and roll out without disrupting live production work.
• Own agentic workflows end to end, from discovery through launch, validation, and iteration: translate a stakeholder team's needs into a phased workflow, decide where AI agents act and where people stay in the loop, and make sure the result is accurate, auditable, and efficient at scale.
• Deliver usable outputs to stakeholder teams across the business: agree on what a finished output looks like and how success is measured, confirm it is used in their work, and close the loop when it is not.
• Partner with the AI scientists and engineers to take agent prototypes to production: weigh evaluation results for user and stakeholder impact, decide how much autonomy a workflow is ready for, and own the pilot, rollout, and success metric.
• Own the onboarding playbook for new user groups, including internal teams and vendor partners: access and roles, training cases in the test environment, team-lead setup, and support materials.
• Plan user-facing releases so changes are tested, communicated, and adopted, with documentation and training built alongside clinical leads.
• Replace manual work with self-service: own the user experience and rollout of an in-platform workflows and drive adoption of self-service project setup by delivery teams.
• Define and track KPIs; use those metrics to guide priorities.
• Own what happens after launch: measure adoption, iterate, and retire workarounds and manual processes once the product replaces them.

Skills

Product management

Workflow software

Agentic AI

SQL

Agile / Jira

User research

UX design

Stakeholder comms

Education

Bachelor's degree or equivalent practical experience

5+ years product management experience

Tools

Jira

Job description

Natera’s Real-World Data ClinicalAI team seeks a product manager who will own the end-to-end experience for the platform used by clinicians and data scientists, translating stakeholder needs into reliable automation.

You will shadow users, write requirements, and drive ideas to rollout, partnering with engineering, QA, and clinical teams to improve efficiency and output quality.

If you enjoy turning complex workflows into simple interfaces and measuring adoption with KPIs, this role will suit you.