Senior Process Engineer, Oligonucleotide Manufacturing

Illumina; San Diego (CA); On-site; USD 98,000 - 148,000; Full time

Benefits offered by this job

Genomics sequencing access

Family planning benefits

Health/dental/vision insurance

Retirement benefits

Paid time off

Job summary

Illumina is seeking driven Process Engineers to join the Manufacturing Technology & Transfer team within Global Operations. You will develop and deploy oligonucleotide manufacturing processes and partner with development, Quality, Production, and Supply Chain teams in a GMP setting.

Responsibilities include executing feasibility builds, creating production equipment requirements, authoring procedures, and training operators to manufacture products.

Qualifications

• Minimum 5 years oligonucleotide experience with a Bachelor’s degree; or 3+ years with a Master’s; or PhD without chemistry/biochemistry/chemical engineering experience.
• Experience with cGMP and 21 CFR Part 11 in an FDA-regulated environment.
• Strong cross-functional collaboration and communication skills.
• Experience with DOE and Statistical Process Control.

Responsibilities

• Execute feasibility and development oligonucleotide builds to support project timelines.
• Define technical requirements for new production equipment and processes.
• Author procedures and train operators for GMP manufacturing.
• Troubleshoot yield, quality and throughput issues in production.
• Conduct DOE-based experiments to optimize processes and scale for production.
• Analyze results, write reports and propose process improvements.
• Collaborate with Product Development, Supply Chain, Manufacturing, Quality, EHS and Facilities.
• Ensure knowledge transfer to manufacturing and sustaining teams.

Skills

Oligonucleotide synthesis

Oligonucleotide QC

HPLC

DOE

cGMP

21 CFR 11

Statistical Process Control

Cross-functional collaboration

Education

Bachelor’s degree in Chemistry/Biochemistry/Chemical Engineering

Tools

Synthesis equipment

HPLC systems

MS instruments

UV spectrometers

Job description

Illumina is seeking driven Process Engineers to join the Manufacturing Technology & Transfer team within Global Operations. You will develop and deploy oligonucleotide manufacturing processes and partner with development, Quality, Production, and Supply Chain teams in a GMP setting.

Responsibilities include executing feasibility builds, creating production equipment requirements, authoring procedures, and training operators to manufacture products.