Senior Principal Scientist, QC - Gene Therapy

Eli Lilly; Lebanon (IN); Sur place; USD 66 000 - 97 000; Plein temps

Avantages offerts par ce poste

Company bonus

401(k)

Pension

Vacation benefits

Medical, dental, vision benefits

Résumé du poste

Lilly is building a cutting-edge facility in Lebanon, Indiana, to manufacture gene therapy and advanced therapy products. The Sr. Principal Chemist supports QC labs, develops analytical methods, and ensures readiness for post-start operations.

You will execute assays, transfer methods, and troubleshoot issues while partnering with Quality Assurance, Manufacturing Science, and external partners to ensure timely, compliant testing delivery. Compensation reflects senior-level responsibilities.

Qualifications

• Bachelor's degree in chemistry, biochemistry, molecular biology, or another related science discipline.
• 7+ years of advanced therapy experience in one or more of the following: gene therapy, LVV, LNP, AAV.

Responsabilités

• Serve as a site SME for gene therapy analytical methods and provide technical guidance.
• Support method transfer, qualification, and validation for new acquisitions and internal development streams.
• Execute assays in in-process, release, and stability testing with data integrity and GMP compliance.
• Support site readiness, equipment/method readiness, and lifecycle management of methods.
• Collaborate with cross-functional teams to align testing strategies for new and existing products.
• Author/review technical documents and support inspections as a SME; mentor lab staff.

Connaissances

Analytical testing

Gene therapy methods

qPCR/ddPCR

ELISA

Capsid characterization

Cell-based potency assays

Root Cause Analysis

Technical SME

Cross-functional influence

Formation

Bachelor's degree in chemistry/biochemistry/molecular biology or related science

Outils

ddPCR/qPCR

ELISA

Description du poste

Lilly is building a cutting-edge facility in Lebanon, Indiana, to manufacture gene therapy and advanced therapy products. The Sr. Principal Chemist supports QC labs, develops analytical methods, and ensures readiness for post-start operations.

You will execute assays, transfer methods, and troubleshoot issues while partnering with Quality Assurance, Manufacturing Science, and external partners to ensure timely, compliant testing delivery. Compensation reflects senior-level responsibilities.