Senior Principal Research Scientist

BioSpace; Irvine (CA); On-site; USD 180,000 - 240,000; Full time

Job summary

A leading biopharmaceutical company is seeking a Senior Principal Research Scientist to lead analytical teams and develop regulatory strategies for peptide drugs. The ideal candidate will have extensive experience in analytical chemistry and demonstrate strong leadership abilities. This role offers an opportunity to significantly impact drug development and regulatory compliance, contributing to innovative solutions in healthcare.

Qualifications

• 18+ years of related industry experience for B.S., 16+ for M.S., or 10+ for Ph.D.
• Strong leadership and collaborative skills.
• In-depth experience with analytical techniques for peptide characterization.
• Experience with global regulatory expectations and regulatory filings in the peptide space

Responsibilities

• Lead analytical teams for drug substance and product development.
• Develop global regulatory strategies and submissions.
• Mentor scientific staff and foster knowledge sharing.
• Coordinate cross-functional teams to deliver robust control strategies for starting materials, intermediates, and products.
• Mentor and develop scientific staff; drive innovation through external networks and collaboration.

Skills

Analytical techniques for peptide characterization

Leadership and mentorship

Interpersonal and communication skills

Problem-solving

Mentoring

Communication

Education

Bachelors, Masters, or PhD in Analytical Chemistry

Tools

HPLC

SEC

Chiral analysis

Amino acid analysis

Peptide mapping

Job description

Overview

Join to apply for the Senior Principal Research Scientist role at BioSpace

AbbVie's mission is to discover and deliver innovative medicines and solutions that solve serious health issues today and address the medical challenges of tomorrow. We strive to have a remarkable impact on people's lives across several key therapeutic areas immunology, oncology, neuroscience, and eye care and products and services in our Allergan Aesthetics portfolio.

For more information about AbbVie, please visit us at www.abbvie.com. Follow @abbvie on X, Facebook, Instagram, YouTube, LinkedIn and TikTok.

Key Responsibilities

• The candidate will lead analytical teams associated with drug substance and drug product development and characterization of peptides and other modalities.
• Leverage prior experience leading analytical efforts focused on phase appropriate peptide drug substance and drug product development.
• Experience developing global regulatory strategies including authoring regulatory submissions, and responding to regulatory questions across global markets.
• Lead across functions within project teams to deliver robust control strategies for starting materials, intermediates, drug substances and drug products.
• Proactively drives innovation by leveraging external networks, industry insights, and prior experiences to identify emerging trends, foster strategic partnerships, and implement forward-thinking solutions.
• Responsible for fit-for purpose method development, testing procedures, justifying specifications, and implementation of analytical control strategies to help the advancement of candidate molecules.
• Proactively advise and share knowledge and expert opinions with subordinates, peers, and senior management.
• Mentor and develop scientific staff in troubleshooting strategic and experimental issues and foster a culture of knowledge sharing.
• The position involves multi-disciplinary collaborations across Discovery, Development, Manufacturing, and Regulatory to execute and deliver material and information for clinical trials and regulatory submissions.
• The candidate will identify and nurture ideas for continuous improvement activities and initiatives within the department.
• This role may include management of direct reports.

Qualifications

• Bachelors, Masters, or PhD in Analytical Chemistry with a minimum of 18+ (B.S.), 16+ (M.S.), or 10+ (Ph.D.) years of related industry experience (advanced degree in Analytical Chemistry preferred). Experience with analytical aspects of advancing peptide modalities.
• Proven scientific leadership; strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to represent analytical in cross-functional development teams.
• In depth experience with analytical techniques required for peptide characterization, such as HPLC, SEC, chiral, amino acid analysis, peptide content, impurity identification, peptide mapping etc.
• Demonstrated leadership of technical teams and effective cross-functional communication
• Demonstrated capability to solve critical scientific and business problems
• Demonstrated ability to implement and to grow the capabilities of an analytical organization and develop scientists into future leaders
• Demonstrated experience with global regulatory expectations and regulatory filings in the peptide space.

Key AbbVie Competencies

• Interacts well with diverse groups within function and maintain strong working relationships with internal and external collaborators to enable higher performance.
• Learns fast, grasps the "essence" and can change course quickly where indicated.
• Raises the bar and is never satisfied with the status quo.
• Creates a learning environment, open to suggestions and experimentation for improvement.
• Embraces the ideas of others, nurtures innovation and manages innovation to reality.

AbbVie is an equal opportunity employer and is committed to operating with integrity, driving innovation, transforming lives and serving our community. Equal Opportunity Employer/Veterans/Disabled.

US & Puerto Rico only - to learn more, visit https://www.abbvie.com/join-us/equal-employment-opportunity-employer.html

US & Puerto Rico applicants seeking a reasonable accommodation, click here to learn more: https://www.abbvie.com/join-us/reasonable-accommodations.html