Lead Peptide Chemistry Scientist

ABBVIE; North Chicago (IL); On-site; USD 125,000 - 237,000; Full time

Job summary

AbbVie in North Chicago, IL is seeking a Principal Research Scientist I, Peptide Chemistry to lead cross-functional project teams in manufacturing process development, characterization, and technology transfer for peptide modalities.

The role requires an SME in peptide processes, collaboration across chemistry, engineering and regulatory groups, authorship of scientific reports and patents, and potential mentoring of junior scientists. A PhD with extensive experience is expected.

Qualifications

• Bachelor’s Degree or equivalent education and typically 14+ years of experience; master’s degree or equivalent education and typically 12+ years of experience; PhD and typically 6+ years of experience in organic chemistry with a focus on peptide synthesis.
• Experience in peptide process development and commercialization.
• A broad range of functional expertise in modern organic chemistry, mechanistic understanding, compound purification, control strategy development and standard analytical methodology (e.g., HPLC, UPLC, LC-MS, NMR).
• Demonstrated scientific communication and presentation skills. Experienced and demonstrated success as author of publications, presentations, and/or primary inventor of patents.
• Strong interpersonal and communication skills for facilitating collaborations and a demonstrated ability to lead cross-functional process development teams.

Responsibilities

• Effectively functions as a principal investigator, generating original technical ideas and demonstrating creative 'out of the box' thinking to solve difficult problems and champion new technologies to achieve project goals. Make significant contributions to project team through lab-based activities. Independently responsible for project science within his/her area of expertise on one or more project teams.
• Authors and/or reviews technical reports, manufacturing batch records and regulatory documents concerning Chemistry, Manufacturing and Control (CMC) subjects. Primary author of publications, presentations, and/or primary inventor of patents.
• Potential to mentor/supervise a team of one or more individuals, evaluate the performance of those individuals and be accountable for the effective performance of those individuals.
• Generate new scientific proposals and lead those efforts. Anticipate and critically evaluate scientific or regulatory advances or competitive threats and respond with appropriate new strategies.
• Interfacing with Manufacturing Operations, Regulatory Affairs, Quality Assurance, etc.

Skills

Peptide processes

Project leadership

Regulatory documentation

Cross-functional collaboration

Mentoring

Education

Bachelor’s degree or equivalent

Master’s degree or equivalent

PhD in organic chemistry (peptide synthesis)

Tools

HPLC

UPLC

LC-MS

NMR

Job description

AbbVie in North Chicago, IL is seeking a Principal Research Scientist I, Peptide Chemistry to lead cross-functional project teams in manufacturing process development, characterization, and technology transfer for peptide modalities.

The role requires an SME in peptide processes, collaboration across chemistry, engineering and regulatory groups, authorship of scientific reports and patents, and potential mentoring of junior scientists. A PhD with extensive experience is expected.