Senior Principal AI Scientist — Biomedical Foundations

Pfizer Inc; United States; Hybrid; USD 139,000 - 232,000; Full time

Job summary

Pfizer Inc. seeks a Senior Principal Machine Learning Scientist to advance AI across drug discovery and development.

You will design, implement, and rigorously evaluate foundation models, multimodal learning, and agentic systems that translate into scientific insights and tangible impact on patients. Working with AI researchers, computational biologists, and engineers, you will own model components, benchmarks, and evaluation pipelines at scale, design reproducible experiments, and communicate

Qualifications

• PhD and 2+ years of experience in Machine Learning, AI, CS, Statistics or related field preferred.
• A Master's degree with 5+ years of industry/research experience is also acceptable.

Responsibilities

• Develop, extend, or evaluate machine learning methods for hard, high-value problems.
• Design rigorous, hypothesis-driven experiments and reproducible research.
• Translate research insights into meaningful outcomes and recommendations across Pfizer R&D.

Skills

Python

PyTorch

JAX

Experiment design

Reproducible research

Education

PhD

Master's degree

Tools

Distributed training

Experiment tracking

Job description

Pfizer Inc. seeks a Senior Principal Machine Learning Scientist to advance AI across drug discovery and development.

You will design, implement, and rigorously evaluate foundation models, multimodal learning, and agentic systems that translate into scientific insights and tangible impact on patients. Working with AI researchers, computational biologists, and engineers, you will own model components, benchmarks, and evaluation pipelines at scale, design reproducible experiments, and communicate