Senior AI Systems Architect for Biomedical Discovery

Pfizer Inc; United States; Hybrid; USD 139,000 - 232,000; Full time

Job summary

Pfizer Inc. is seeking a Senior Principal AI Research Engineer to own end-to-end AI capabilities—from architecture to deployment—supporting scientists across discovery, development, and translational science.

You will build secure, scalable systems that accelerate biomedical insights in a hybrid US-based model. Collaborating with AI scientists, data engineers, and platform teams, you will balance performance, security, and maintainability while driving measurable outcomes and responsible AI

Qualifications

• PhD or equivalent with demonstrated software/ML experience (2+ years).
• Strong programming skills in Python and ML frameworks.
• Experience delivering production systems in cloud or distributed environments.
• Ability to work across interdisciplinary teams.

Responsibilities

• Design, develop, and deploy production-grade AI systems for multimodal biomedical models.
• Engineer data pipelines, retrieval systems, evaluation frameworks, and knowledge systems.
• Translate scientific needs into technical solutions and deliver end-to-end platforms.

Skills

Python

PyTorch

JAX

Software architecture

APIs & testing

CI/CD

Distributed GPU training

Education

PhD in Computer Science/Engineering/Applied Math or related

Master's with 5+ years of relevant experience

Bachelor's with 6+ years of relevant experience

Tools

Docker

Kubernetes

Git

PyTorch

JAX

Job description

Pfizer Inc. is seeking a Senior Principal AI Research Engineer to own end-to-end AI capabilities—from architecture to deployment—supporting scientists across discovery, development, and translational science.

You will build secure, scalable systems that accelerate biomedical insights in a hybrid US-based model. Collaborating with AI scientists, data engineers, and platform teams, you will balance performance, security, and maintainability while driving measurable outcomes and responsible AI