Senior OT & Manufacturing Systems Manager

Axogen; Vandalia (OH); On-site; USD 114,000 - 142,000; Full time

Benefits offered by this job

Health insurance

Dental insurance

Vision insurance

Matching 401K

Paid time off

Floating holidays

Employee stock purchase plan

Tuition reimbursement

Paid parental leave

Disability insurance

Job summary

Axogen is seeking a Manager, Operational Technology & Manufacturing Systems in Vandalia, OH to lead the OT and IT landscape for the Ohio manufacturing facility. The role partners with plant leadership and Corporate IT to ensure reliable operations and regulatory compliance.

You will manage OT, infrastructure, cybersecurity, and manufacturing applications while coordinating with production, quality, validation, and engineering to align technology with business goals and capacity expansion.

Qualifications

• Bachelor’s degree or 8 years of related experience in IT/OT leadership.
• Minimum 7 years supporting enterprise, OT, or regulated systems.
• Minimum 3 years leading technical teams and managing vendors.
• Experience with regulated production environments, validation, and compliance docs.
• Strong communication and cross-functional collaboration skills.
• Preferred knowledge of GxP, 21 CFR Part 11, data integrity, and cybersecurity.

Responsibilities

• Lead onsite OT and IT teams and align technology with business priorities.
• Oversee maintenance, lifecycle management, and audit readiness of manufacturing tech.
• Drive site growth, infrastructure modernization, and digital transformation.
• Govern changes, validation activities, CAPA, and change control with stakeholders.

Skills

Bachelor’s/Engineering background

OT/Manufacturing systems

Leadership of technical teams

Vendor management

Regulated environments

Cybersecurity basics

GxP/21 CFR Part 11 familiarity

Education

Bachelor’s degree in Information Systems / CS / Engineering / Biotechnology or related

Job description

Axogen is seeking a Manager, Operational Technology & Manufacturing Systems in Vandalia, OH to lead the OT and IT landscape for the Ohio manufacturing facility. The role partners with plant leadership and Corporate IT to ensure reliable operations and regulatory compliance.

You will manage OT, infrastructure, cybersecurity, and manufacturing applications while coordinating with production, quality, validation, and engineering to align technology with business goals and capacity expansion.