Senior OSD Process Engineer — Process Transfer & Optimization

Syner-G; Newark (DE); On-site; USD 140,000 - 180,000; Full time

Benefits offered by this job

Fully remote work options

Office locations: Greater Boston, San-

Job summary

Syner-G seeks a Senior Process Engineer with 8+ years in oral solid dose manufacturing to lead process optimization and commercial support. The role partners with MSAT, QA, and Engineering to enhance robustness, efficiency, and compliance across granulation, compression, coating, and packaging operations.

You will drive technology transfer from development to production, troubleshoot complex issues, and mentor junior engineers while ensuring GMP compliance and program success.

Qualifications

• BS or MS in Chemical Engineering, Mechanical Engineering, Pharmaceutical Engineering, or a related technical field.

Responsibilities

• Lead process optimization for oral solid dose manufacturing processes, including granulation, compression, coating, and packaging.
• Support technology transfer activities from development and pilot operations into commercial manufacturing, ensuring process scalability, robustness, and reproducibility.
• Troubleshoot process deviations, yield losses, equipment challenges, and cycle time constraints in commercial OSD manufacturing environments.
• Provide technical support for process validation activities, including PPQ execution and continued process verification.
• Collaborate closely with MSAT, Manufacturing, Quality, and Engineering teams to resolve technical issues and implement sustainable process improvements.
• Develop and maintain process documentation such as process descriptions, equipment specifications, risk assessments, and technical reports.
• Conduct data analysis and performance trending to identify root causes, variability drivers, and improvement opportunities.
• Support commissioning, qualification, and start-up activities for OSD manufacturing equipment.
• Drive continuous improvement initiatives focused on throughput, yield, cost reduction, and GMP compliance.
• Mentor and support junior engineers by providing technical guidance and process expertise.

Skills

GMP knowledge

Cross-functional collaboration

Root cause analysis

Process controls

Communication skills

Education

BS or MS in Chemical Engineering, Mechanical Engineering, Pharmaceutical Engineering, or related field

Tools

Tablet presses

Granulators

Fluid bed systems

Coating equipment

Job description

Syner-G seeks a Senior Process Engineer with 8+ years in oral solid dose manufacturing to lead process optimization and commercial support. The role partners with MSAT, QA, and Engineering to enhance robustness, efficiency, and compliance across granulation, compression, coating, and packaging operations.

You will drive technology transfer from development to production, troubleshoot complex issues, and mentor junior engineers while ensuring GMP compliance and program success.