Senior Oncology Lab Director – Lead High-Impact Diagnostics

BillionToOne; Edison (CA); On-site; USD 247,000 - 268,000; Full time

Benefits offered by this job

Equity options

Generous benefits package

On-site lunches

Job summary

BillionToOne is seeking a Senior Laboratory Director, Oncology to lead the daily operations of our high-complexity oncology clinical laboratory in Menlo Park, CA. Reporting to the SVP of Laboratory Operations, you will own the lab's end‑to‑end operations, including quality, TAT, capacity, cost, and regulatory compliance, with 2–3 onsite days per week.

You will build and scale the oncology lab, manage headcount, budget, and procurement, and oversee variant interpretation and sign-out from

Qualifications

• Doctoral degree in genetics, molecular biology, or related field with board certification
• CA CLD license eligibility and NY CoQ in oncology testing
• 7+ years in a regulated clinical lab with 4+ years in molecular oncology testing including NGS
• Experience leading oncology assay development/validation and cancer genomics knowledge

Responsibilities

• Lead oncology lab organization including headcount planning and competency management
• Own the oncology lab budget, COGS, operating expenses, and capital equipment planning
• Drive turnaround time, throughput, capacity, and quality targets with process improvements
• Oversee lab scale-up, assay onboarding, inspections, and procurement
• Ensure somatic variant interpretation and oncology report sign-out accuracy

Skills

Leadership

Budgeting / P&L

Regulatory compliance

Project management

Communication

Laboratory operations

Education

Doctoral degree (PhD, MD, or equivalent)

Board Certification (ABMGG, ABP)

Licensure eligibility (CA CLD) / NY CoQ

Tools

LIMS

IGV

BAM file review

Oncology bioinformatics tools

COSMIC / OncoKB / ClinVar databases

Job description

BillionToOne is seeking a Senior Laboratory Director, Oncology to lead the daily operations of our high-complexity oncology clinical laboratory in Menlo Park, CA. Reporting to the SVP of Laboratory Operations, you will own the lab's end‑to‑end operations, including quality, TAT, capacity, cost, and regulatory compliance, with 2–3 onsite days per week.

You will build and scale the oncology lab, manage headcount, budget, and procurement, and oversee variant interpretation and sign-out from