Senior Neuroimmunology Scientist CNS Translational Discovery

Merck; Boston (MA); Vor Ort; USD 119.000 - 188.000; Vollzeit

Zusammenfassung

Merck seeks a laboratory-based scientist to join the Neuroimmunology team in Massachusetts, Boston. The role focuses on hands‑on experimental work across preclinical models and translational biology to uncover microglial mechanisms and advance CNS therapies.

You will design and execute in vitro and in vivo studies, analyze complex data, and contribute to program strategy while collaborating with pharmacology, immunology, chemistry, and biomarker scientists.

Qualifikationen

• PhD in Neuroscience, Immunology, Cell Biology, Pharmacology, Bioengineering, Neurology, or a related STEM field; postdoctoral industry experience highly preferred.
• Master's degree in Neuroscience, Immunology, Cell Biology, Pharmacology, Bioengineering, Neurology, or a related STEM field with a minimum 8+ years of pharmaceutical or biotechnology industry experience.
• Extensive hands‑on experience with rodent in vivo studies.
• Experience with mouse models of neurodegeneration, neuroinflammation, or CNS disease.
• Expertise in flow cytometry, CNS immune cell isolation, immunohistochemistry, and molecular biology techniques.
• Proficiency with omics approaches (RNA‑seq, single‑cell technologies) and data analysis.
• Strong experimental design, statistical analysis, and problem‑solving skills.
• Excellent communication and collaboration skills in a cross‑functional research environment.

Aufgaben

• Serve as a hands‑on scientist conducting in vitro and in vivo procedures and downstream analyses.
• Play a key role in supporting pipeline programs by designing and executing studies, interpreting complex datasets, and communicating findings to cross‑functional teams.
• Generate and interpret pharmacology, efficacy, biomarker, and mechanistic datasets to support target validation and drug discovery programs.
• Perform CNS immune cell isolation, flow cytometry, immunophenotyping, molecular profiling, and histological analyses.
• Collaborate with multidisciplinary teams across pharmacology, immunology, chemistry, biologics, biomarker sciences, and data science.
• The individual is expected to provide strong scientific leadership, contribute to program strategy, and influence decision‑making through data‑driven recommendations.

Kenntnisse

Rodent in vivo studies

Mouse models of neurodegeneration

Flow cytometry

Molecular biology techniques

Omics data analysis

Experimental design & statistics

Communication & collaboration

Ausbildung

PhD in Neuroscience/Immunology/Cell Biology/Pharmacology/Bioengineering/Neurology or related STEM field

Master's degree with 8+ years pharma/biotech industry experience

Tools

Flow cytometry

Immunohistochemistry

Molecular profiling

RNA-seq

Single-cell technologies

Jobbeschreibung

Merck seeks a laboratory-based scientist to join the Neuroimmunology team in Massachusetts, Boston. The role focuses on hands‑on experimental work across preclinical models and translational biology to uncover microglial mechanisms and advance CNS therapies.

You will design and execute in vitro and in vivo studies, analyze complex data, and contribute to program strategy while collaborating with pharmacology, immunology, chemistry, and biomarker scientists.